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TranscriptomicsAnalysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant
We expressed either a wt or a phosphomutant version of ZFP36L1 in IMR90 ER:RAS cells. 7 days upon RAS induction (when the cells reach a fully senescent phenotype) we collected the RNA. ZFP36L1 is a RNA binding protein that binds to AU-rich elements in the 3’UTR of mRNAs and triggers their degradat...
ORGANISM(S): Homo sapiens 
2015-07-07 | E-GEOD-61130 | biostudies-arrayexpress
UnknownIdentification of the genetic mechanism that associates L3MBTL3 to multiple sclerosis.
Not available
S-EPMC9262392 | biostudies-literature
UnknownEvaluation of the prehospital diagnostic accuracy of a novel point-of-care test for NT-proBNP, D-dimer and H-FABP and large-vessel occlusion risk assessment (LVOCheck-EVA): a protocol for a multicenter prospective observational study in patients suspected of having a stroke.
Not available
S-EPMC12719076 | biostudies-literature
UnknownSecreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.
Not available
S-EPMC9705309 | biostudies-literature
TranscriptomicsSenescent and myofibroblastic cancer-associated fibroblasts share a contractile phenotype regulated by NOX4 generation of reactive oxygen species in the tumour microenvironment
Cancer associated fibroblasts characterized by an myofibroblastic phenotype play a major role in the tumour microenvironment, being associated with poor prognosis. We found that this cell population is made in part by senescent fibroblasts in vivo. As senescent fibroblasts and myofibroblasts have be...
ORGANISM(S): Homo sapiens 
2017-06-01 | E-MTAB-3101 | biostudies-arrayexpress
UnknownCOVID-19 and the impact of arterial hypertension-An analysis of the international HOPE COVID-19 Registry (Italy-Spain-Germany).
Not available
S-EPMC8420356 | biostudies-literature
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
TranscriptomicsINTEGRATIVE ONCOGENOMIC AND HIGH-THROUGHPUT SEQUENCING ANALYSES OF THE COMMONLY DELETED REGION IN CHROMOSOME 7q32 IN SPLENIC MARGINAL ZONE LYMPHOMA (SNP data)
Using high-resolution genomic microarray analysis, a distinct genomic profile was defined in 114 samples from patients with splenic marginal zone lymphoma (SMZL). Notably, deletion or uniparental disomy of chromosome 7q were detected in 39% of SMZLs but in only 9 of 170 (5%) mature B-cell lymphomas ...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-35329 | biostudies-arrayexpress
UnknownDiverse Large HIV-1 Non-subtype B Clusters Are Spreading Among Men Who Have Sex With Men in Spain.
Not available
S-EPMC6457325 | biostudies-literature
UnknownUNIversity students' LIFEstyle behaviours and Mental health cohort (UNILIFE-M): study protocol of a multicentre, prospective cohort study.
Not available
S-EPMC12815070 | biostudies-literature
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