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UnknownStomach cancer risk after treatment for hodgkin lymphoma.
Not available
S-EPMC3770865 | biostudies-literature
UnknownEnantioselective approach to quinolizidines: total synthesis of cermizine D and formal syntheses of senepodine G and cermizine C.
Not available
S-EPMC3711505 | biostudies-literature
UnknownToward a unified approach for the lycopodines: synthesis of 10-hydroxylycopodine, deacetylpaniculine, and paniculine.
Not available
S-EPMC3616490 | biostudies-literature
TranscriptomicsMicrocolony formation by the opportunistic pathogen Pseudomonas aeruginosa requires pyruvate and pyruvate fermentation.
A hallmark of the biofilm architecture is the presence of microcolonies. However, little is known about the underlying mechanisms governing microcolony formation. In the human pathogen Pseudomonas aeruginosa, microcolony formation is dependent on the two-component regulator MifR, with mifR mutant bi...
ORGANISM(S): Pseudomonas aeruginosa 
2012-04-30 | E-GEOD-35286 | biostudies-arrayexpress
TranscriptomicsPseudomonas aeruginosa two-component regulator BfmR controls bacteriophage lysis and DNA release during biofilm development through PhdA
Biofilms are surface-adhered bacterial communities encased in an extracellular matrix composed of polysaccharides, proteins, and extracelluar (e)DNA, with eDNA being required for the formation and integrity of biofilms. Here we demonstrate that the spatial and temporal release of eDNA is regulated b...
ORGANISM(S): Pseudomonas aeruginosa 
2011-06-01 | E-GEOD-28953 | biostudies-arrayexpress
MetabolomicsSmall Polar Hits against S. aureus: Screening, Initial Hit Optimization, and Metabolomic Studies
The global prevalence of antibacterial resistance requires new antibacterial drugs with novel chemical scaffolds and modes of action. It is also vital to design compounds with optimal physicochemical properties to permeate the bacterial cell envelope. We described an approach of combining and integr...
2021-11-04 | MTBLS788 | MetaboLights
ProteomicsACSS2 Upregulation Enhances Neuronal Resilience to Aging and Neurodegeneration
Epigenetic mechanisms, including histone acetylation, play a key role in learning and memory, with recent evidence of a role in neuronal function in Alzheimer’s disease and Related Dementia (ADRD). Acetyl-CoA sythetase 2 (ACSS2) is central to epigenetics and gene regulation, particularly in neurons,...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD048769 | Pride
Acss2 Aging Neuron Neurodegeneration 
UnknownSynthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells.
Not available
S-EPMC9650275 | biostudies-literature
UnknownMonocyte-derived transcriptome signature indicates antibody-dependent cellular phagocytosis as a potential mechanism of vaccine-induced protection against HIV-1.
Not available
S-EPMC8514236 | biostudies-literature
GenomicsHistone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [ChIP-Seq]
Variation in chromatin composition and organization often reflects differences in genome function. Histone variants, for example, replace canonical histones to contribute to regulation of numerous nuclear processes including transcription, DNA repair and chromosome segregation. Here we focus on H2A....
ORGANISM(S): Homo sapiens 
2012-07-16 | E-GEOD-38284 | biostudies-arrayexpress
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