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TranscriptomicsMembers of the Entamoeba histolytica transmembrane kinase family play non-redundant roles in growth and phagocytosis
Entamoeba histolytica contains a large and novel family of transmembrane kinases (TMK) with proposed roles that include both amebic response to the environment and immune evasion. In the later case, the process requires several elements --these include a large gene family encoding antigenically dist...
ORGANISM(S): Entamoeba histolytica 
2010-11-01 | E-GEOD-19064 | biostudies-arrayexpress
TranscriptomicsChanges in the transcriptome of Entamoeba histolytica accompany the epigenetic silencing of the amoebapore gene.
We previously showed that epigenetic transcriptional silencing of the amoebapore gene (Ehap-a) in E. histolytica G3 trophozoites was accompanied by the down-regulation of two other members of the saposin-like gene family (Ehap-b, and EhSaplip1). Comparison of the transcriptomes of G3 trophozoites w...
ORGANISM(S): Entamoeba histolytica 
2011-08-30 | E-GEOD-28883 | biostudies-arrayexpress
TranscriptomicsTargets of the E. histolytica transcription factor URE3-BP
The E. histolytica transcription factor URE3-BP is a calcium-responsive regulator of two E. histolytica virulence genes, hgl5 and fdx1. URE3-BP was previously identified by a yeast one-hybrid screen of E. histolytica proteins capable of binding to the sequence TATTCTATT (URE3) in the promoter region...
ORGANISM(S): Entamoeba histolytica 
2008-10-14 | E-GEOD-12188 | biostudies-arrayexpress
TranscriptomicsCharacterization of an Entamoeba histolytica High-Mobility-Group Box Protein Induced during Intestinal Infection
The unicellular eukaryote Entamoeba histolytica is a human parasite that causes amebic dysentery and liver abscess. A genome-wide analysis of gene expression modulated by intestinal colonization and invasion identified an up-regulated transcript that encoded a putative high-mobility-group box (HMGB)...
ORGANISM(S): Entamoeba histolytica 
2008-11-19 | E-GEOD-12204 | biostudies-arrayexpress
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
UnknownWhole-genome sequencing reveals host factors underlying critical COVID-19.
Not available
S-EPMC9259496 | biostudies-literature
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