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Aim: To provide an exploratory proteomic characterization of periodontal disease-related immune pathways by analyzing gingival crevicular fluid, revealing subtle proteomic changes accompanying disease progression. Materials and methods: Gingival crevicular fluid samples were collected from normal (c...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD065250 | Pride
Inflammatory periodontal disease (periodontitis) is widespread in dogs. This study aimed to evaluate site-specific changes in the canine gingival crevicular fluid (GCF) proteome during the longitudinal progression from very mild gingivitis to mild periodontitis. Periodontitis diagnosis in dogs requi...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2016-03-21 | PXD003337 | Pride
Oral polymorphonuclear neutrophils (oPMNs) are essential for the maintenance of oral health. Functionally active oPMNs have been described in oral health, gingivitis and periodontitis. Interestingly, recent evidence showed that oPMNs from chronic periodontitis patients have a similar functional and ...
ORGANISM(S): Homo sapiens 
2020-09-01 | GSE118304 | GEO
Transcriptome dynamics of oral polymorphonuclear neutrophils during experimental gingivitis
A longitudinal study of the oral microbiome during the onset and resolution of experimentally-induced gingivitis
We used phylogenetic low-density microarrays targeting the 16S rRNA gene to characterize the gingival flora of acute noma and acute necrotizing gingivitis lesions, and compared them to healthy control subjects of the same geographical and social background. Various types of samples were collected (c...
ORGANISM(S): human oral metagenome 
P&G gingivitis Metagenome
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