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ProteomicsLongitudinal quantification of the GCF proteome during progression from gingivitis to periodontitis in a canine model
Inflammatory periodontal disease (periodontitis) is widespread in dogs. This study aimed to evaluate site-specific changes in the canine gingival crevicular fluid (GCF) proteome during the longitudinal progression from very mild gingivitis to mild periodontitis. Periodontitis diagnosis in dogs requi...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2016-03-21 | PXD003337 | Pride
Gcf Gingivitis Canine Periodontitis 
GenomicsStreptomyces tunisiensis strain:GCF 039538125 | isolate:Streptomyces tunisiensis
Streptomyces tunisiensis strain:GCF 039538125 | isolate:Streptomyces tunisiensis Genome sequencing
PRJNA1251220 | ENA
ProteomicsComparative Proteomic Signatures in Periodontitis: Saliva, Gingival Crevicular Fluid (GCF), Plaque, vs. Serum
Saliva, gingival crevicular fluid (GCF), and serum are common sources for studying host response and oral microbiota in periodontal patients. This cross-sectional study aimed to compare the proteomic signatures of periodontitis patients using full-mouth periodontal sampling with those obtained from...
ORGANISM(S): Homo sapiens (Human) 
2025-10-27 | PXD055509 | Pride
Gcf Serum Saliva Periodontitis 
ProteomicsComparative Proteomics of Tissue and Gingival Crevicular Fluid in Periodontitis
Periodontitis is an inflammatory condition affecting periodontal tissues, such as the gingiva and alveolar bone, surrounding the teeth. However, previous research has focused on analyzing a single sample type, such as tissue, blood, or gingival crevicular fluid (GCF), which may limit the comprehensi...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD054953 | Pride
Proteomics Periodontitis Neutrophil Gcf Systemic inflammation 
ProteomicsGingival exudatome dynamics implicates inhibition of the alternative complement pathway in the protective action of the C3 inhibitor Cp40 in non-human primate periodontitis
Complement inhibition has been successfully used to treat periodontitis in animal models. However, proteome studies that investigated the role of complement C3 were missing. The objective of this study was to characterize local tissue exudate (“gingival crevicular fluid”; GCF) changes after administ...
ORGANISM(S): Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) 
2018-08-17 | PXD009502 | Pride
C3 inhibitor Gcf Periodontitis Macaca fascicularis 
GenomicsAcanthosepion esculentum isolate:GCF-2018
Acanthosepion esculentum isolate:GCF-2018 Genome sequencing and assembly
PRJNA557338 | ENA
UnknownGenetic Control of GCF Exudation: Innate Immunity Genes and Periodontitis Susceptibility.
Not available
S-EPMC10532312 | biostudies-literature
TranscriptomicsSpecified Bacterial Species in Gingival Crevicular Fluid Predict Diversity of Unattached Subgingival Microbiota
Analysis of gingival crevicular fluid (GCF) samples may give information of the identity of unattached (planktonic) subgingival bacteria, the 35 forefront candidates for systemic dispersal via ulcerated periodontal pocket epithelium. Our study represents the first one targeting the identity of bact...
ORGANISM(S): Homo sapiens 
2010-05-21 | E-GEOD-21929 | biostudies-arrayexpress
UnknownA synthetic BBB-permeable tripeptide GCF confers neuroprotection by increasing glycine in the ischemic brain.
Not available
S-EPMC9420865 | biostudies-literature
UnknownIdentification and regulation of a novel Citrobacter rodentium gut colonization fimbria (Gcf).
Not available
S-EPMC4372744 | biostudies-literature
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