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UnknownConsensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2.
Not available
S-EPMC3319201 | biostudies-literature
TranscriptomicsTherapeutic potential of a novel HSP90 Inhibitor, NXD30001, for Neurofibromatosis type 2
Purpose: The growth and survival of NF2-deficient cells are enhanced by the activation of multiple signaling pathways including ErbB2/IGF-1R/Met, PI3K/Akt, and Ras/Raf/Mek/Erk1/2. The ubiquitously expressed chaperone protein HSP90 is known to be essential for the stabilization of these signaling mol...
ORGANISM(S): Mus musculus 
2013-06-06 | E-GEOD-40187 | biostudies-arrayexpress
UnknownConjunctival Extramedullary Plasmacytoma in Dogs and a Cat: Clinical Characteristics and Histopathological Findings.
Not available
S-EPMC9653729 | biostudies-literature
TranscriptomicsMerlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4DCAF1 in the Nucleus
Current models imply that the FERM domain protein Merlin, encoded by the tumor suppressor NF2, inhibits mitogenic signaling at or near the plasma membrane. Here, we show that the closed, growth inhibitory form of Merlin accumulates in the nucleus, binds to the E3 ubiquitin ligase CRL4DCAF1, and supp...
ORGANISM(S): Mus musculus 
2010-03-09 | E-GEOD-19305 | biostudies-arrayexpress
UnknownGut-Brain Axis: Insights from Hippocampal Neurogenesis and Brain Tumor Development in a Mouse Model of Experimental Colitis Induced by Dextran Sodium Sulfate.
Not available
S-EPMC9569494 | biostudies-literature
UnknownUsing ultrasound to define inflammatory and non-inflammatory phenotypes in difficult-to-treat psoriatic arthritis
Not available
S-EPMC12352194 | biostudies-literature
TranscriptomicsExpression analysis of YAP and Angiomotin target genes
To assess changes in gene expression regulated by Yap1 or Angiomotin, either Yap1 or Angiomotin were knocked down in HEK293 cells using shRNA and expression was assessed by microarray analysis and compared to expression patterns of wildtype cells. Microarray analysis was performed to compare gene...
ORGANISM(S): Homo sapiens 
2013-10-21 | E-GEOD-49406 | biostudies-arrayexpress
UnknownIntubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries.
Not available
S-EPMC7988368 | biostudies-literature
UnknownCurrent whole-body MRI applications in the neurofibromatoses: NF1, NF2, and schwannomatosis.
Not available
S-EPMC5578359 | biostudies-literature
UnknownAssociation of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes.
Not available
S-EPMC6280443 | biostudies-literature
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