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ProteomicsThe interferon-inducible antiviral GTPase MxB promotes capsid disassembly and genome release of herpesviruses
Host proteins sense viral products and induce defense mechanisms, particularly in immune cells. Using cell-free assays and quantitative mass spectrometry, we determined the interactomes of capsidhost protein complexes of herpes simplex virus, and identified the large dynamin-like GTPase myxovirus re...
ORGANISM(S): Homo sapiens (Human) Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) 
2022-05-06 | PXD028276 | Pride
Hsv1   mxb   host defense 
ProteomicsHuman cytomegalovirus-induced host protein citrullination is crucial for viral replication
Citrullination is the conversion of arginine-to-citrulline by protein arginine deiminases (PADs), whose dysregulation is implicated in the pathogenesis of various types of cancers and autoimmune diseases. Consistent with the ability of human cytomegalovirus (HCMV) to induce post-translational modifi...
ORGANISM(S): Homo sapiens (Human) 
2021-07-20 | PXD025803 | Pride
Hcmv Ifit1 Citrullination 
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