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TranscriptomicsTranscription profiling of MIII celiac disease patients vs controls (M0) individuals
Comparison of MIII celiac disease patients to controls (M0) individuals.
ORGANISM(S): Homo sapiens 
2005-01-01 | E-MEXP-42 | biostudies-arrayexpress
TranscriptomicsTranscript profiling of individual twin blastomeres derived by splitting 2-cell stage murine embryos
We have examined whether twin blastomeres from 2-cell stage mouse embryos differ in mRNA content. Amplified mRNA from 12 blastomeres derived from six embryos approximately mid-way through their second cell cycle was analyzed. Probes displaying normalized values greater than 0.25 were selected and ex...
ORGANISM(S): Mus musculus 
2010-05-28 | E-GEOD-21688 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of B7.5 lineage cells in the tunicate Ciona intestinalis to study cardiac cell migration
Eight different types of sample (three samples each) were used in this study of cardiac cell migration in the tunicate Ciona intestinalis. The B7.5 lineage cells were isolated by Fluorescent Activated Cell Sorting (FACS) at the tailbud stage, when the cardiac precursors (anterior B7.5 lineage cells)...
ORGANISM(S): Ciona intestinalis 
2008-06-01 | E-MEXP-1478 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human neurofibromatosis type 1
Genes involved in tumorigenesis associated with neurofibromatosis type 1.
ORGANISM(S): Homo sapiens 
2007-01-12 | E-TABM-69 | biostudies-arrayexpress
MetabolomicsIsotopomer analysis of MCF-7 breast cancer cell line incubated with 13C labelled glucose (NMR assay)
MS and NMR are two of the most powerful spectroscopic techniques used in the field of fluxomics, to analyze the flux distributions in cellular metabolomic pathways. Both of them possess pros and cons, such as, MS being the most sensitive and low-cost technique, while needs extensive sample processin...
2018-05-02 | MTBLS241 | MetaboLights
TranscriptomicsComparative genomic hybridization of Clostridium sporogenes and Clostridium botulinum strains
Clostridium botulinum is a heterogeneous Gram-positive species that comprises four genetically and physiologically distinct groups of bacteria that share the ability to produce botulinum neurotoxin, the most poisonous toxin known to man, and the causative agent of botulism, a severe disease of human...
ORGANISM(S): Clostridium botulinum 
2007-05-23 | E-TABM-264 | biostudies-arrayexpress
TranscriptomicsMARS-seq Version 2
scRNA-seq procedure and analysis. ScRNA-seq was performed using the Massively Parallel Single-Cell RNA-sequencing technology (MARS-seq) as described by Jaitin et al., 2014 (PMID: 24531970) EpiSCs were seeded at ~6 x 103 cells/cm2 in 6-well cell-culture plates pre-coated with 15 µg/ml human Fibronec...
ORGANISM(S): Mus musculus 
2025-04-28 | E-MTAB-13660 | biostudies-arrayexpress
GenomicsWhole Genome Bisulfite Sequencing of CLDN6High vs CLDN6Low Sorted EpiSCs and APSD, and WT vs Pbx1-KO EpiSCs
The experiment was designed to assess the DNA methylation differences between CLDN6Low vs CLDN6High EpiSCs and APSD, as well as WT vs Pbx1-KO EpiSCs. Based on analysis of RNAseq data and GO, we narrowed down our focus to DNA methylation effects influencing lineage biases. We performed WGBS analysi...
ORGANISM(S): Mus musculus 
2025-04-28 | E-MTAB-13574 | biostudies-arrayexpress
TranscriptomicsAltered Gene Expression in Human Adipose Stem Cells Cultured with Fetal Bovine Serum Compared to Human Supplements
Mesenchymal stromal cells (MSCs) are promising candidates for innovative cell therapeutic applications. For clinical scale manufacturing regulatory agencies recommend to replace fetal bovine serum (FBS) commonly used in MSC expansion media as soon as equivalent alternative supplements are available....
ORGANISM(S): Homo sapiens 
2010-08-28 | E-GEOD-23851 | biostudies-arrayexpress
TranscriptomicsA positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B mono-ubiquitylation to regulate transcript elongation in fission yeast
Transcript elongation by RNA polymerase II (RNAPII) is accompanied by conserved patterns of histone modification within transcribed regions, but it remains uncertain how these modifications influence, or are influenced by, properties of the elongation complex. Here we establish an intimate link betw...
ORGANISM(S): Schizosaccharomyces pombe 
2012-12-01 | E-GEOD-31070 | biostudies-arrayexpress
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