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TranscriptomicsDiscovery of novel hypermethylated gene loci in prostate cancer using genome wide coverage CpG island microarrays
In order to identify methylation changes in prostate cancer, we performed a genome-wide analysis of DNA methylation using Agilent human CpG island arrays. We then chose specific genes to validate methylation both in the same cases as were hybridized to the array (using quantitative EpiTYPER analysis...
ORGANISM(S): Homo sapiens 
2009-03-26 | E-GEOD-15298 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human prostate cancer between african-american and european-american men
The incidence and mortality rates of prostate cancer are significantly higher in African-American men when compared to European-American men. We tested the hypothesis that differences in tumor biology contribute to this survival health disparity. Using microarray technology, we obtained gene express...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6956 | biostudies-arrayexpress
TranscriptomicsCells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations
Prostate cancer-associated stroma (CAS) plays an active role in malignant transformation, tumor progression, and metastasis. Molecular analyses of CAS have demonstrated significant changes in gene expression; however, conflicting evidence exists on whether genomic alterations in benign cells compris...
ORGANISM(S): Homo sapiens 
2016-02-12 | E-GEOD-76456 | biostudies-arrayexpress
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