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MetabolomicsGlobal Metabonomic and Proteomic Analysis of Human Conjunctival Epithelial Cells (IOBA-NHC) in Response to Hyperosmotic Stress
“Dry eye” is a multi-factorial inflammatory disease affecting the ocular surface. Tear hyperosmolarity in dry eye contributes to inflammation and cell damage. Recent research efforts on dry eye have been directed towards biomarker discovery for diagnosis, response to treatment and disease mechanisms...
2015-08-31 | MTBLS214 | MetaboLights
MetabolomicsIntegrated Metabolomics and Transcriptomics Suggest the Global Metabolic Response to 2-Aminoacrylate Stress in Salmonella enterica
Not available
ORGANISM(S): Salmonella enterica 
ST001305 | MetabolomicsWorkbench
MetabolomicsGlobal ocean lipidomes show a universal relationship between temperature and lipid unsaturation

Global-scale surveys of plankton communities using “omics” techniques have revolutionized our understanding of the ocean. Lipidomics has demonstrated the potential to add further essential insights on ocean ecosystem function but has yet to be applied on a global scale. We analyzed 930 lipid samp...

2021-11-08 | MTBLS2838 | MetaboLights
MetabolomicsMulti-omics reveals the response and adaptation of Acidithiobacillus ferrooxidans BY-3 under arsenic stress
Acidithiobacillus ferrooxidans exhibits arsenic resistance and plays a significant role in biometallurgy and sulfur cycling within ecosystems. This study employed integrated transcriptomic, proteomic, and metabolomic analyses to investigate the molecular response mechanisms of Acidithiobacillus ferr...
2026-09-03 | MTBLS15537 | MetaboLights
MetabolomicsGlobal metabolomics of fireflies (Coleoptera: Lampyridae) explore metabolic adaptation to fresh water in insects

Aquatic insects are well-adapted to freshwater environments, but metabolic mechanisms of such adaptations, particularly to primary environmental factors (e.g., hypoxia, water pressure, dark light and abundant microbes), are poorly known. Most firefly species (Coleoptera: Lampyridae) are terrestri...

2022-10-03 | MTBLS4987 | MetaboLights
MetabolomicsMultiomic analysis revealed the potential role of rumen microbes in heat stress

Heat stress is an important issue in dairy cattle feeding management affecting summer health and economic efficiency. In recent years, global climate change has led to an increase in atmospheric CO2 content and average daily temperature, making heat stress a major challenge in dairy farming. This...

2022-08-11 | MTBLS5132 | MetaboLights
MetabolomicsTranscriptomic and metabolomic comparison of two Kandelia obovata cultivas in response to cold wave
Temperature is the primary environmental factor that restricts the growth and distribution of mangrove plants. With the escalating severity of global climate change, Kandelia obovata has gained widespread recognition as an ideal species for investigating the response mechanisms of mangroves to cold ...
2024-09-27 | MTBLS9845 | MetaboLights
TranscriptomicsThe rsa3-1 mutation affects global gene expression in Arabidopsis thaliana under salt stress.
Salt stress is one of the most severe environmental conditions which cause huge losses in crop production worldwide. We identified an essential regulator of salt stress RSA3 and used the Affymetrix whole-genome arrays to study the effect of rsa3-1 mutation on global gene expression under salt stress...
ORGANISM(S): Arabidopsis thaliana 
2013-04-20 | E-GEOD-41626 | biostudies-arrayexpress
TranscriptomicsThe rsa1-1 mutation affects global gene expression in Arabidopsis thaliana with or without salt stress
Salt stress is one of the most severe environmental conditions which cause huge losses in crop production worldwide. We identified a novel calcium-binding protein and used the Affymetrix whole-genome arrays to define downstream targets of this important protein. We used the microarrays to reveal the...
ORGANISM(S): Arabidopsis thaliana 
2013-07-07 | E-GEOD-39236 | biostudies-arrayexpress
MetabolomicsEffect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages

Global climate change has led to an increase in release of atmospheric CO2 and average daily temperatures, making heat stress a major challenge in dairy farming. The present study aimed to investigate metabolite changes of Holstein cows at different stages. In this experiment, 10 growing heifers,...

2022-08-11 | MTBLS5148 | MetaboLights
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