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ProteomicsGlomerular filtrate proteins in acute cardiorenal syndrome
Acute cardiorenal syndrome (CRS-1) is a morbid complication of acute cardiovascular disease. Mechanistic investigations have focused on intrarenal cellular signaling induced by ischemia/reperfusion. Additional signals, “cardiorenal connectors”, have been postulated, but investigation in CRS-1 has ...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-27 | PXD012148 | Pride
Glomerular filtrate Nanoproteomics Acute cardiorenal syndrome Kidney 
ProteomicsGlomerular filtrate proteins in acute cardiorenal syndrome
Acute cardiorenal syndrome (CRS-1) is a morbid complication of acute cardiovascular disease. Mechanistic investigations have focused on intrarenal cellular signaling induced by ischemia/reperfusion. Additional cardiorenal connector signals have been postulated, but investigation in CRS-1 has been li...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-27 | PXD012193 | Pride
Cardiovascular disease Urine Isobaric labeling Mouse model Acute cardiorenal syndrome Quantitative proteomics Tandem mass tags 
ProteomicsMouse kidney glomerular extracellular matrix LC-MSMS
Across the spectrum of human disease there are significant changes in the composition and organisation of extracellular matrix (ECM). Furthermore, disease severity can vary according to race and sex, yet mechanisms for these variations are unclear. Using the kidney glomerulus as a model system, we t...
ORGANISM(S): Mus musculus (Mouse) 
2016-07-09 | PXD000811 | Pride
Lc-msms Mouse Kidney Glomerular Extracellular matrix 
UnknownGlomerular filtrate proteins in acute cardiorenal syndrome.
Not available
S-EPMC6478405 | biostudies-literature
UnknownPredictive effect of estimated glomerular filtrate rate by creatinine or cystatin C on mortality in patients with coronary artery disease.
Not available
S-EPMC10993740 | biostudies-literature
UnknownThe Glomerular Endothelium Restricts Albumin Filtration.
Not available
S-EPMC8667033 | biostudies-literature
UnknownEstimation of the Cadmium Nephrotoxicity Threshold from Loss of Glomerular Filtration Rate and Albuminuria.
Not available
S-EPMC10534899 | biostudies-literature
UnknownPolygenic association of glomerular filtration rate decline in world trade center responders.
Not available
S-EPMC9615399 | biostudies-literature
TranscriptomicsTranscriptional profiling of the zebrafish proximal tubule
The proximal tubules of the kidney carry out the bulk of solute reabsorption from the glomerular filtrate. They are also highly susceptible to damage as a result of diabetes or other syndromes that affect the kidney. The zebrafish embryonic/larval form of kidney, the pronephros, represents a simplif...
ORGANISM(S): Danio rerio 
2019-06-05 | GSE95808 | GEO
TranscriptomicsThe soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo
The endocytic receptor megalin constitutes the main pathway for clearance of plasma proteins from the glomerular filtrate in the proximal tubules. However, little is know about the mechanisms that control receptor activity. A widely discussed hypothesis states that the intracellular domain (ICD) of ...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-19778 | biostudies-arrayexpress
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