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In order to characterize defense responses not only cytologically, but also on the transcript level, genome-wide sequencing of mRNA isolated from non-infected control leaves and from leaves inoculated either with the WT or with GLS1 overexpressing strains was performed, using Illumina Next Generatio...
ORGANISM(S): Zea mays 
Glutaminase (GLS1) is involved in the development of Alcoholic liver disease (ALD). Protein-protein interactions underlie the biological processes impacted by GLS1. we used immunoprecipitation-mass spectrometry (IP-MS) technology and found the proteins interacted with GLS1.
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD050603 | Pride
Metabolic reprogramming modulates cardiomyocyte hypertrophy via GLS1 in chronic kidney disease
GLS1 governs vascular smooth muscle cell phenotypic switching and aortic dissection via glutamate metabolism
scRNAseq analysis of kidney treated with GLS1 inhibitor [scRNA-seq Kid_BPTES]
scRNAseq analysis of lung treated with GLS1 inhibitor [scRNA-seq Lung_BPTES]
The role of GLS1 and MPC2 in germinal center B cell regulation
Left ventricular hypertrophy (LVH) is critical in chronic kidney disease (CKD), but its mechanisms remain unclear. This study employed multi-omics approaches, including RNA-seq and integrated metabolomics, to characterize metabolic alterations in cardiomyocytes (CM) of CKD mice, revealing enhanced g...
ORGANISM(S): Mus musculus 
2026-08-13 | GSE343701 | GEO
To evaluate the roles of glutaminase 1 (GLS1) in vascular smooth muscle cells (VSMCs) phenotypic switching and aortic dissection (AD). Integrative transcriptomic analyses were performed to identify the candidate genes involved in VSMC phenotypic switching in AD. The expression of GLS1 in VSMCs was a...
ORGANISM(S): Homo sapiens 
2026-03-20 | GSE324926 | GEO
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