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TranscriptomicsGlycan effect on Saccharolytic Human Distal Gut Symbiont, B. thetaiotaomicron
This SuperSeries is composed of the following subset Series: GSE11944: Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont GSE11953: Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont: ECF ...
ORGANISM(S): Bacteroides thetaiotaomicron 
2008-11-20 | E-GEOD-11980 | biostudies-arrayexpress
MetabolomicsN-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression
Various cancers such as colorectal cancer (CRC) are associated with alterations in protein glycosylation. CRC cell lines are frequently used to study these (glyco)biological changes and their mechanisms. However, differences between CRC cell lines with regard to their glycosylation have hitherto bee...
2017-02-03 | MTBLS227 | MetaboLights
GenomicsXBP1s Activation Globally Remodels N-Glycan Structure Distribution Patterns
XBP1s Activation Globally Remodels N-Glycan Structure Distribution Patterns
PRJNA448415 | ENA
TranscriptomicsMucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont
Gene expression profiles of Bacteroides thetaiotaomicron in vitro during growth on host mucosal polysaccharides as sole carbon sources. All substrates in this series are derived from porcine gastric mucin and include mucin O-glycans and glycosaminoglycans. Two different culture formats used: 800ml b...
ORGANISM(S): Bacteroides thetaiotaomicron 
2008-11-20 | E-GEOD-11944 | biostudies-arrayexpress
TranscriptomicsMucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont: ECF mutant
Growth of isogenic parent ('tdk strain'), 5xECF-sigma factor mutant and complemented mutant strain in the cecum of NMRI inbred mice fed a glycan-restricted, 'simple sugar' diet (35% each glucose and sucrose). Bacteria were collected from mouse distal gut 10 days after colonization. Experiment perfor...
ORGANISM(S): Bacteroides thetaiotaomicron 
2008-11-20 | E-GEOD-11953 | biostudies-arrayexpress
ProteomicsGlycan Markers of Human Stem Cells Assigned with Beam Search Arrays
Glycan antigens recognized by monoclonal antibodies have served as stem cell markers. To understand regulation of their biosynthesis and their roles in stem cell behavior precise assignments are required. We have applied state-of-the-art glycan array technologies to compare the glycans bound by five...
ORGANISM(S): Cellular Organisms 
2019-06-18 | PXD013972 | JPOST Repository
ProteomicsPrecision mapping of glycosite-specific glycans reveals distinctive N-glycosylation on human spermatozoa
In this study, we applied the recently developed software, StrucGP to large-scale characterize glycoproteins, and IGPs, as well as precise site-specific glycan structures in human spermatozoa. Furthermore, bioinformatical analyses were conducted to systematically describe the potential functions of ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-19 | PXD026649 | Pride
Spermatozoa Glycan structures Mass spectrometry 
ProteomicsElucidation of the glycan structure of the b-type flagellin of Pseudomonas aeruginosa PAO1
Flagella are essential for motility and pathogenicity in many bacteria. The main component of the flagellar filament, flagellin, often undergoes post-translational modifications, with glycosylation being a common occurrence. In Pseudomonas aeruginosa PAO1, the b-type flagellin is O-glycosylated with...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2025-05-07 | PXD056085 | Pride
Glycosylation Mass spectrometry (ms) Proteomics Cell motility Bacteria Pseudomonas 
ProteomicsStructural Interpretation of Glycosite-specific N-Glycans Using Tandem Mass Spectrometry
In this project we developed a new algorithm termed StrucGP, for large-scale interpretation of N-glycan structures on intact glycopeptides from tandem mass spectrometry data. StrucGP is able to reveal the glycan structure heterogeneity for individual glycosites. The StrucGP also has high performance...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Mus musculus (Mouse) Gallus gallus (Chicken) 
2021-07-07 | PXD025859 | Pride
N-glycans Intact glycopeptides Glycan structure 
TranscriptomicsGrowth of B. thetaiotaomicron on purified host mucosal glycans and glycan fragments
Bacteroides thetaiotaomicron was grown and transcriptionally profiled on a number of different host mucosal glycans and their component mono- and disaccharides. Experiments are performed in biological duplicate (2 replicates per growth condition). All cultures were harvested at similar points in mid...
ORGANISM(S): Bacteroides thetaiotaomicron 
2008-11-20 | E-GEOD-11962 | biostudies-arrayexpress
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