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ProteomicsProteomic analysis of glycosomes from Leishmania donovani
Leishmania donovani is a kinetoplastid protozoan which causes Kala-azar or visceral leishmaniasis.Leishmania possess glycosomes that are unique and specialized subcellular microbody organelles. Glycosomes are known to harbor most peroxisomal enzymes and in addition they also possess glycolytic enzym...
ORGANISM(S): Leishmania donovani 
2015-03-25 | PXD000724 | Pride
Leishmaniasis Subcellular organelle Kinetoplastid 
UnknownProteomic analysis of glycosomes from Trypanosoma cruzi epimastigotes.
Not available
S-EPMC7082770 | biostudies-literature
UnknownComprehensive proteomics analysis of glycosomes from Leishmania donovani.
Not available
S-EPMC4356261 | biostudies-literature
UnknownA Global Analysis of Enzyme Compartmentalization to Glycosomes.
Not available
S-EPMC7237986 | biostudies-literature
ProteomicsNucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei
In Trypanosoma brucei, there are fourteen enzymatic biotransformations that collectively convert glucose into five essential nucleotide sugars: UDP-Glc, UDP-Gal, UDP-GlcNAc, GDP-Man and GDP-Fuc. These biotransformations are catalyzed by thirteen discrete enzymes, five of which possess putative perox...
ORGANISM(S): Trypanosoma brucei 
2021-01-28 | PXD023124 | Pride
Nucleotide sugar biosynthesis Glycosome localization T. brucei 
ProteomicsThe trypanosome UDP-glucose pyrophosphorylase is active in both the glycosomal and cytosolic compartments and is imported into glycosomes by piggybacking
Trypanosoma brucei, the etiological agent of sleeping sickness, has particular peroxisome-like organelles called glycosomes where several metabolic pathways are compartmentalized, including glycolysis. Many enzymes from sugar nucleotide biosynthetic pathways are located in this organelle, contrastin...
ORGANISM(S): Trypanosoma brucei 
2021-06-10 | PXD020190 | Pride
Trypanosoma brucei Label-free quantitative proteome analysis 
UnknownIron superoxide dismutases targeted to the glycosomes of Leishmania chagasi are important for survival.
Not available
S-EPMC201062 | biostudies-literature
UnknownThe Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place.
Not available
S-EPMC8262884 | biostudies-literature
UnknownNucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei.
Not available
S-EPMC7909634 | biostudies-literature
TranscriptomicsGene expression profiling of Trypanosoma cruzi in the presence of heme points to glycosomal metabolic adaptation of epimastigotes inside the vector
Using the Deep Seq transcriptome sequencing we characterized the heme induced transcriptome of epimastigotes and determined that most of the upregulated genes were related to glucose metabolism inside the glycosomes.
ORGANISM(S): Trypanosoma cruzi 
2021-04-21 | GSE172452 | GEO
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