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MetabolomicsMetabolic fingerprinting reveals roles of Arabidopsis thaliana BGLU1, BGLU3, and BGLU4 in glycosylation of various flavonoids

Flavonoids are specialized metabolites that play important roles in plants, including interactions with the environment. The high structural diversity of this metabolite group is largely due to enzyme-mediated modifications of flavonoid core skeletons. In particular, glycosylation with different ...

2025-02-25 | MTBLS1965 | MetaboLights
TranscriptomicsH. pylori G27 HP0518 mutant showed greater motility
Helicobacter pylori is a human gastric pathogen associated with gastric and duodenal ulcers as well as specific gastric cancers. It is well-evidenced that motility is essential for this pathogen to colonize human gastric tissues. We found that the H. pylori G27 HP0518 mutant showed greater motility ...
ORGANISM(S): Helicobacter pylori 
2010-12-22 | E-GEOD-14752 | biostudies-arrayexpress
MetabolomicsThe glycosyltransferase UGT76B1 modulates N-hydroxy-pipecolic acid homeostasis and plant immunity
The trade-off between growth and defense is a critical aspect of plant immunity. Therefore, the plant immune response needs to be tightly regulated. Salicylic acid (SA) is an important plant hormone regulating defense against biotrophic pathogens. Recently, N-hydroxy-pipecolic acid (NHP) was identif...
2022-02-28 | MTBLS2334 | MetaboLights
GenomicsO-GlcNAcylation Modulates Expression and Abundance of N-Glycosylation Machinery in an Inherited Glycosylation Disorder
O-GlcNAcylation Modulates Expression and Abundance of N-Glycosylation Machinery in an Inherited Glycosylation Disorder
PRJNA1120060 | ENA
ProteomicsImproving statistical certainty of glycosylation similarity between influenza A virus variants using data-independent acquisition mass spectrometry
The amino acid sequences of immunodominant domains of hemagglutinin (HA) on the surface of influenza A virus (IAV) evolve rapidly, producing viral variants. HA mediates receptor recognition, binding and cell entry, and serves as the target for IAV vaccines. Glycosylation, a post-translational modifi...
ORGANISM(S): Homo sapiens (Human) Canis familiaris (Dog) (Canis lupus familiaris) Gallus gallus (Chicken) 
2022-09-24 | PXD029700 | Pride
Influenza Dia Glycoproteomics Mass spectrometry Glycosylation similarity Hemagglutinin 
GenomicsWhole-genome CRISPR screening identifies N-glycosylation as an essential pathway and a potential novel therapeutic target in CALR-mutant MPN (Pooled CRISPR Screen).
Whole-genome CRISPR screening identifies N-glycosylation as an essential pathway and a potential novel therapeutic target in CALR-mutant MPN (Pooled CRISPR Screen).
PRJNA840897 | ENA
ProteomicsDirect comparison between a Burkholderia cenocepacia glycosylation mutant strain, and a glycosylation knockdown strain
To determine whether CRISPR interference can be used to recapitulate a glycosylation null mutant strain in Burkholderia cenocepacia via data independent acquisition mass spectrometry
ORGANISM(S): Burkholderia cenocepacia K56-2Valvano 
2023-03-20 | PXD037550 | Pride
Glycosylation Burkholderia cenocepacia Dia Crispr interference Crispri 
UnknownOverexpression of Mutant FKRP Restores Functional Glycosylation and Improves Dystrophic Phenotype in FKRP Mutant Mice.
Not available
S-EPMC5992437 | biostudies-literature
GenomicsWhole-genome CRISPR screening identifies N-glycosylation as an essential pathway and a potential novel therapeutic target in CALR-mutant MPN (Whole Genome CRISPR Screen).
Whole-genome CRISPR screening identifies N-glycosylation as an essential pathway and a potential novel therapeutic target in CALR-mutant MPN (Whole Genome CRISPR Screen).
PRJNA840899 | ENA
OtherWhole-genome CRISPR screening identifies N-glycosylation as an essential pathway and a potential novel therapeutic target in CALR-mutant MPN (Pooled CRISPR Screen).
Calreticulin (CALR) mutations are frequent, disease-initiating events in myeloproliferative neoplasms (MPN). Although the biological mechanism by which CALR mutations cause MPN has been elucidated, there currently are no clonally selective therapies for CALR-mutant MPN. To identify unique genetic de...
ORGANISM(S): Mus musculus 
2022-09-21 | GSE203455 | GEO
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