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MetabolomicsMicrobial liberation of N-methylserotonin from orange fiber in gnotobiotic mice and humans
Plant fibers in byproduct streams produced by non-harsh food processing methods represent biorepositories of diverse, naturally occurring, and physiologically active biomolecules. To demonstrate one approach for their characterization, mass spectrometry of intestinal contents from gnotobiotic mice, ...
2022-07-28 | MTBLS2331 | MetaboLights
MetabolomicsComparing Campylobacter jejuni to three other enteric pathogens in OligoMM 12 mice reveals pathogen-specific host and microbiota responses
Campylobacter jejuni, non-typhoidal Salmonella spp., Listeria monocytogenes and enteropathogenic/enterohemorrhagic Escherichia coli (EPEC/EHEC) are leading causes of food-borne illness worldwide. Citrobacter rodentium has been used to model EPEC and EHEC infection ...
2025-02-25 | MTBLS11078 | MetaboLights
TranscriptomicsThe impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. (COPRO-Seq)
Understanding how the human gut microbiota and host are impacted by probiotic bacterial strains requires carefully controlled studies in humans, and in mouse models of the gut ecosystem where potentially confounding variables that are difficult to control in humans can be constrained. Therefore, we ...
ORGANISM(S): Bacteria 
2011-11-01 | E-GEOD-31943 | biostudies-arrayexpress
GenomicsGnotobiotic mice
Metagenomic analyses of laboratory gnotobiotic mice
PRJEB105017 | ENA
MetabolomicsCecal metabolome of gnotobiotic (containing a 14-member synthetic human gut microbiota), and germ-free mice fed with two distinct rodent diets with varying fiber content.
Not available
ORGANISM(S): Mus musculus 
ST002172 | MetabolomicsWorkbench
TranscriptomicsExpression data from stomach of germ-free and gnotobiotic mice
The aim of this study was to examine the role of indigenous lactobacilli in the physiological development of the stomach in mice using microarray analysis. In lactobacilli-associated gnotobiotic mice, an increased expression of the genes related to the muscle system development, such as nebulin and ...
ORGANISM(S): Mus musculus 
2011-04-28 | E-GEOD-28895 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse gnotobiotic ileum, listeria infection series
Ileal profiles from gnotobiotic mice mono-associated with Listeria species or B. thetaiotaomicron. Samples were derived from 72h colonizations of Fabpi-hEcad transgenic B6 mice fed a standard-chow polysaccharide rich (PR) diet. Experiment Overall Design: Total RNA was prepared from ileum of 72 ho...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7013 | biostudies-arrayexpress
MetabolomicsContribution of fungal microbiome to intestinal physiology, early-life immune development and mucosal inflammation in mice
The gut microbiome consists of a multi-kingdom microbial community. Whilst the role of bacteria as causal contributors governing host physiological development is well established, the role of fungi remains to be determined. Here, we use germ-free mice colonized with defined species of bacteria, fun...
2022-01-14 | MTBLS1679 | MetaboLights
ProteomicsMetaproteomic Profiling of Functional Changes Driven by Gut Fungal Colonization
Gut microbiome modulates the host immune development, yet the functional contribution of gut fungi remains elusive. We previously showed that mice colonized only with fungi displayed allergic features and fecal metabolite profiles similar to germ-free mice. To gain insights into the functional chang...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-28 | PXD019355 | Pride
Gut fungi Early-life gut microbiome Lfq and tmt proteomics Gnotobiotic mice 
TranscriptomicsThe impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. (RNA-Seq)
Understanding how the human gut microbiota and host are impacted by probiotic bacterial strains requires carefully controlled studies in humans, and in mouse models of the gut ecosystem where potentially confounding variables that are difficult to control in humans can be constrained. Therefore, we ...
ORGANISM(S): Lactococcus lactis subsp. cremoris CNCM I-1631 
2011-11-01 | E-GEOD-31670 | biostudies-arrayexpress
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