Sort   by:  
 Page size 
TranscriptomicsFunction, targets and evolution of Caenorhabditis elegans piRNAs
This SuperSeries is composed of the following subset Series: GSE28617: Function, targets and evolution of Caenorhabditis elegans piRNAs (small RNA-Seq) GSE37432: Function, targets and evolution of Caenorhabditis elegans piRNAs (mRNA) Refer to individual Series
ORGANISM(S): Caenorhabditis elegans 
2012-06-17 | E-GEOD-37433 | biostudies-arrayexpress
TranscriptomicsmiR-124 acts through coREST to control the onset of Sema3A sensitivity in navigating retinal growth cones
During axon pathfinding, growth cones commonly exhibit changes in sensitivity to guidance cues that follow a strict timetable, even in the absence of pathway feedback, implicating cell-intrinsic regulation. Cellular timer mechanisms, however, are poorly understood. Here we have investigated microRNA...
ORGANISM(S): Xenopus laevis 
2011-12-12 | E-GEOD-33444 | biostudies-arrayexpress
TranscriptomicsThe microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans
We generated animals carrying a genomically integrated mir-124 promoter::gfp transgene and identified mir-124 promoter::GFP labelled cells as a subset of the C. elegans sensory neurons. We used fluorescence activated cell sorting (FACS) to isolate four distinct cell populations: mir-124 expressing (...
ORGANISM(S): Caenorhabditis elegans 
2010-03-22 | E-GEOD-16050 | biostudies-arrayexpress
TranscriptomicsFunction, targets and evolution of Caenorhabditis elegans piRNAs (mRNA)
piRNAs are required to maintain germline integrity and fertility but their mechanism of action is poorly understood. Here we demonstrate that C. elegans piRNAs silence transcripts in trans through imperfectly complementary sites. We find that target silencing is independent of Piwi endonuclease acti...
ORGANISM(S): Caenorhabditis elegans 
2012-06-17 | E-GEOD-37432 | biostudies-arrayexpress
GenomicsMassively parallel nanowell-based single-cell gene expression profiling
Technological advances have enabled transcriptome characterization of cell types at the single-cell level providing new biological insights. New methods that enable simple yet high-throughput single-cell expression profiling are highly desirable. Here we report a novel nanowell-based single-cell RNA...
EGAS00001002320 | EGA
TranscriptomicsFunction, targets and evolution of Caenorhabditis elegans piRNAs (small RNA-Seq)
piRNAs are required to maintain germline integrity and fertility but their mechanism of action is poorly understood. Here we demonstrate that C. elegans piRNAs silence transcripts in trans through imperfectly complementary sites. We find that target silencing is independent of Piwi endonuclease acti...
ORGANISM(S): Caenorhabditis elegans 
2012-06-18 | E-GEOD-28617 | biostudies-arrayexpress
TranscriptomicsCharacterisation of microRNA expression in post-natal mouse mammary gland development
Background: The differential expression pattern of microRNAs (miRNAs) during mammary gland development might provide insights into their role in regulating the homeostasis of the breast epithelium. Our aim was to analyse these regulatory functions by deriving a comprehensive tissue-specific combined...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-15057 | biostudies-arrayexpress
TranscriptomicsCharacterisation of microRNA expression in post-natal mouse mammary gland development [miRNA]
Background: The differential expression pattern of microRNAs (miRNAs) during mammary gland development might provide insights into their role in regulating the homeostasis of the breast epithelium. Our aim was to analyse these regulatory functions by deriving a comprehensive tissue-specific combined...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-15055 | biostudies-arrayexpress
TranscriptomicsCharacterisation of microRNA expression in post-natal mouse mammary gland development [gene]
Background: The differential expression pattern of microRNAs (miRNAs) during mammary gland development might provide insights into their role in regulating the homeostasis of the breast epithelium. Our aim was to analyse these regulatory functions by deriving a comprehensive tissue-specific combined...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-15054 | biostudies-arrayexpress
Genomicsena-DATASET-Genentech-12-07-2017-18:52:38:402-9 - samples
Massively parallel nanowell-based single-cell gene expression profiling
EGAD00001003443 | EGA
Sort   by:  
 Page size