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UnknownAntimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study.
Not available
S-EPMC7334278 | biostudies-literature
TranscriptomicsMouse, pig, and human atherosclerotic lesions have common and distinct mesenchymal cell populations
The single-cell RNA-seq experiment aims to explore the cell-type composition of right coronary artery plaques to provide an overview of human-like atherosclerosis. The PCSK9 transgenic minipigs were subjected to 15 months of HFHC diet (HFHC group f, n=4; m, n=1). At the time of euthanasia, plaque pa...
ORGANISM(S): Sus scrofa 
2025-08-30 | E-MTAB-15464 | biostudies-arrayexpress
MetabolomicsFunctional Characterization of the Lin28/let-7 Circuit During Forelimb Regeneration in Ambystoma mexicanum and Its Influence on Metabolic Reprogramming
The axolotl (Ambystoma mexicanum) is a caudate amphibian, which has an extraordinary ability to restore a wide variety of damaged structures by a process denominated epimorphosis. While the origin and potentiality of progenitor cells that take part during epimorphic regeneration are known to ...
2021-11-04 | MTBLS1708 | MetaboLights
TranscriptomicsTranscriptome comparision in ovaries between sexual and apomictic plants of Brachiaria using cDNA microarrays
Some flowering plants exhibit a phenomenon called apomixis, defined as the ability to produce seeds asexually and with the same genetic constitution as the mother plant. The existence of a genetic basis for apomixis is evident, but the molecular mechanisms that underlie it remain unclear. The search...
ORGANISM(S): Urochloa decumbens 
2011-01-24 | E-GEOD-26837 | biostudies-arrayexpress
MetabolomicsCorrelation-based Deconvolution (CorrDec) to generate high-quality MS2 spectra from data-independent acquisition in multi-sample studies (Urine assay)

Data-independent acquisition mass spectrometry (DIA-MS) is essential for information-rich spectral annotations in untargeted metabolomics. However, the acquired MS2 spectra are highly complex, posing significant annotation challenges. We have developed a correlation-based deconvolution (CorrDec) ...

2020-07-13 | MTBLS816 | MetaboLights
ProteomicsOptimization of Experimental Parameters in Data-Independent Mass Spectrometry Significantly Increases Depth and Reproducibility of Results
Comprehensive, reproducible and precise analysis of large sample cohorts is one of the key objectives of quantitative proteomics. Here, we present an implementation of data-independent acquisition using its parallel acquisition nature that surpasses the limitation of serial MS2 acquisition of data-d...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2020-01-30 | MSV000084874 | MassIVE
ProteomicsIdentification and spectral annotation of the threespine stickleback gill proteome
Gill proteome samples from four populations of threespined sticklebacks; Six biological replicates each for 4 different populations: Bodega Harbor, CA (fully plated, marine), Lake Solano (low-plated, freshwater), Laguna de la Bocana del Rosario, Mexico (low plated, brackish water, warm-adapted), Wes...
ORGANISM(S): Gasterosteus Aculeatus (ncbitaxon:69293) 
2017-12-09 | MSV000081795 | MassIVE
UnknownUncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single-cell resolution.
Not available
S-EPMC9904760 | biostudies-literature
ProteomicsVascular proteome responses precede organ dysfunction in a murine model of Staphylococcus aureus bacteremia
Vascular dysfunction and organ failure are two distinct, albeit highly interconnected clinical outcomes linked to morbidity and mortality in human sepsis. The mechanisms driving vascular and parenchymal damage are dynamic and display significant molecular crosstalk between organs and tissues. Theref...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-03-10 | MSV000089030 | MassIVE
UnknownTomatidine is a senotherapeutic that improves cognitive function and reduces senescence in aged mice
Not available
S-SCDT-10_1038-S44321-026-00400-0 | biostudies-other
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