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TranscriptomicsTargeting the MTOR-AKT pathway in DLBCL
The mTOR (mammalian Target of Rapamycin) pathway is constitutively activated in Diffuse Large B-Cell Lymphoma (DLBCL). mTOR inhibition has been shown to have clinical activity in patients with DLBCL, although overall response rates remain low. We therefore evaluated differences in the transcriptome...
ORGANISM(S): Homo sapiens 
2012-04-29 | E-GEOD-27255 | biostudies-arrayexpress
UnknownConcentration and proteolysis of CX3CL1 may regulate the microglial response to CX3CL1.
Not available
S-EPMC9772123 | biostudies-literature
TranscriptomicsTempo-Seq experiment relating to Next Generation Risk Assessment for Occupational Chemical Safety – a Real World Example with Sodium-2-hydroxyethane sulfonate
A dose response and human cell line comparison of transcriptional responses following treatment with the chemical compound Sodium-2-hydroxyethane sulfonate. Gene expression changes were used to estimate the POD - minimum effect concentration when a biological perturbation as estimated by gene exp...
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-14069 | biostudies-arrayexpress
UnknownA Qualitative Evaluation Exploring Co-Production of Falls Management in Care Homes.
Not available
S-EPMC12630552 | biostudies-literature
UnknownMultiple and multidimensional transitions from trainee to trained doctor: a qualitative longitudinal study in the UK.
Not available
S-EPMC5719319 | biostudies-literature
TranscriptomicsCardiac Resynchronization Therapy (1-color design)
Objectives: To test whether (1) electromechanical dyssynchrony induces region-specific alterations in the myocardial transcriptome and (2) dyssynchrony-induced gene expression changes can be corrected by cardiac resynchronization (CRT). Background: To date, CRT is the only heart failure treatment th...
ORGANISM(S): Canis lupus familiaris 
2010-05-16 | E-GEOD-14327 | biostudies-arrayexpress
UnknownEffectiveness of Acute Care Remote Triage Systems: a Systematic Review.
Not available
S-EPMC7352001 | biostudies-literature
TranscriptomicsThe role of HIF in FH-associated renal neoplasia
Fumarate hydratase (FH) mutations predispose to renal cysts cancer. These cancers overexpress hypoxia-inducible factor-alpha (Hif-1a). We have generated a conditional Fh1 (mouse FH) knockout mice that develop renal cysts and overexpress Hif-1a. In order to identify the contribution of Hif-1a to cyst...
ORGANISM(S): Mus musculus 
2011-10-23 | E-GEOD-29988 | biostudies-arrayexpress
TranscriptomicsAn integrated approach combining RNA-seq, Ribo-seq and Proteomics identifies the coding potential of Mycobacterium abscessus
The objective of this study is to develop an integrated map for the M. abscessus ATCC19977 organism. Among the data types contributing to the development of this map are next-generation RNA-sequencing, differential RNA-sequencing, ribosome profiling, and mass spectrometry. The design of the study co...
ORGANISM(S): Mycobacterium abscessus ATCC 19977 
2016-03-30 | E-GEOD-72996 | biostudies-arrayexpress
UnknownhTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan.
Not available
S-EPMC12341801 | biostudies-literature
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