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TranscriptomicsMolecular markers associated with outcome and metastasis in human pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous cancer in which differences in survival rates might be related to a variety in gene expression profiles. Although the molecular biology of PDAC begins to be revealed, genes or pathways that specifically drive tumour progression or metastasis...
ORGANISM(S): Homo sapiens 
2013-01-09 | E-GEOD-42952 | biostudies-arrayexpress
TranscriptomicsGene expression data from acetaminophen-induced toxicity in human hepatic in vitro systems and clinical liver samples
In this study we conducted transcriptomics analyses of: (i) liver samples from patients suffering from acetaminophen-induced acute liver failure (n=3) and from healthy livers (n=2) and (ii) hepatic cell systems exposed to acetaminophen, including their respective vehicle controls. The investigated i...
ORGANISM(S): Homo sapiens 
2015-11-04 | E-GEOD-74000 | biostudies-arrayexpress
TranscriptomicsThe side population of human pancreatic cancer expresses cancer stem cell-associated genes
Purpose: To explore the side population (SP) in pancreatic ductal adenocarcinoma (PDAC) for its gene expression profile and its association to cancer stem cells (CSC) and to evaluate the value of genes from its gene signature on patient survival. Experimental design: Side and main population (MP) c...
ORGANISM(S): Homo sapiens 
2014-09-26 | E-GEOD-42404 | biostudies-arrayexpress
TranscriptomicsSide population cells in human primary melanoma
Melanoma remains the most lethal skin cancer, mainly because of high resistance to therapy. Side population (SP) cells are found in many types of cancer and are usually enriched in therapy-resistant as well as tumorigenic cells. Here, we identified a Hoechst dye-effluxing SP in a large series of hum...
ORGANISM(S): Homo sapiens 
2014-05-27 | E-GEOD-48838 | biostudies-arrayexpress
TranscriptomicsPituitary tumors contain a (CD31¯/CD45¯ purified) side population with 'tumor stem cell'-associated characteristics [set 2]
Pituitary adenomas cause significant endocrine and mass-related morbidity. Not much is known about mechanisms underlying pituitary tumor pathogenesis. We searched for a side population (SP) in pituitary tumor, representing cells with high efflux capacity and potentially enriching for cancer/tumor st...
ORGANISM(S): Homo sapiens 
2015-08-04 | E-GEOD-62870 | biostudies-arrayexpress
TranscriptomicsPituitary tumors contain a side population with 'tumor stem cell'-associated characteristics [set 1]
Pituitary adenomas cause significant endocrine and mass-related morbidity. Not much is known about mechanisms underlying pituitary tumor pathogenesis.We searched for a side population (SP) in pituitary tumor, representing cells with high efflux capacity and potentially enriching for cancer/tumor ste...
ORGANISM(S): Homo sapiens 
2015-08-04 | E-GEOD-62866 | biostudies-arrayexpress
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