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ProteomicsTMT-based proteome and phosphoproteome profiling of control and GPR146 knockdown SGBS cells
This dataset contains quantitative proteome and phosphoproteome profiles of control and GPR146 knockdown SGBS human preadipocyte cells. Cells were processed for tandem mass tag (TMT)–based multiplexed quantitative mass spectrometry, with parallel analysis of total proteome input samples and TiO2-enr...
ORGANISM(S): Homo sapiens (Human) 
2026-02-19 | PXD074087 | Pride
Phosphoproteomics Gpr146 Sgbs cells Orbitrap Tmt6plex Lc-ms/ms 
GenomicsHepatic gene expression data from Gpr146 WT and KO male mice
Hepatic gene expression data from Gpr146 WT and KO male mice
PRJNA578295 | ENA
UnknownGPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis.
Not available
S-EPMC6889877 | biostudies-literature
TranscriptomicsHepatic gene expression data from Gpr146 WT and KO male mice
GPR146 is a susceptible gene associated with plasma cholesterol levels in humans, its physiological and molecular functions have not been fully characherized. In this study, we generated Gpr146 whole-body knockout mice and found that depletion of GPR146 led to substantilly reduced plasma total chole...
ORGANISM(S): Mus musculus 
2019-11-27 | GSE139082 | GEO
GenomicsHepatic and adipose tissue gene expression profiles from Gpr146 wild-type and knockout male mice
Hepatic and adipose tissue gene expression profiles from Gpr146 wild-type and knockout male mice
PRJNA1401819 | ENA
TranscriptomicsHepatic and adipose tissue gene expression profiles from Gpr146 wild-type and knockout male mice
Metabolic dysfunction–associated steatotic liver disease (MASLD) remains a major health burden with limited therapeutic options. Human genetic studies implicate GPR146, an orphan G protein–coupled receptor, in circulating cholesterol levels and markers of liver injury. In this study, we investigated...
ORGANISM(S): Mus musculus 
2026-01-31 | GSE316218 | GEO
UnknownElucidating the multifaceted roles of GPR146 in non-specific orbital inflammation: a concerted analytical approach through the prisms of bioinformatics and machine learning.
Not available
S-EPMC11188444 | biostudies-literature
GenomicsGPR146 facilitates blood pressure elevation and vascular remodeling via PIEZO1
GPR146 facilitates blood pressure elevation and vascular remodeling via PIEZO1
PRJNA1258913 | ENA
TranscriptomicsCholesin Receptor Signalling is Active in Cardiovascular System-Associated Adipose Tissue and Correlates with SGLT2i Treatment in Patients with Diabetes
Objective: To identify the cholesin receptor-associated genes and clinical factors linked with their expression in cardiovascular system and associated adipose tissues. Research Design and Methods: Right cardiac auricle, aortic wall, saphenous vein and adipose tissue (periaortic-PAT, epicardial-EAT,...
ORGANISM(S): Homo sapiens 
2024-06-20 | GSE263644 | GEO
UnknownCholesin receptor signalling is active in cardiovascular system-associated adipose tissue and correlates with SGLT2i treatment in patients with diabetes.
Not available
S-EPMC11191148 | biostudies-literature
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