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TranscriptomicsGenome-scale RNAi profiling of cell division in human tissue culture cells
Cell division is a fundamental process for multicellula organisation. Here we report a genome-scale RNAi screen in HeLa cells designed to identify human genes important for cell division. We utilized a library of endoribonuclease-prepared siRNAs (esiRNAs) for gene-silencing and used DNA content an...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-9176 | biostudies-arrayexpress
TranscriptomicsCrosstalk between the diseased atherosclerotic aorta and the peripheral nervous system [Ganglion]
The goal of these studies was to delineate mechanisms of crosstalk between the atherosclerotic arterial wall of the aorta and the peripheral nervous system (PNS) in aged hyperlipidemic ApoE-deficient mice. We had observed by immunohistochemistry and morphometry that axon density of the PNS in advent...
ORGANISM(S): Mus musculus 
2022-02-27 | GSE93954 | GEO
TranscriptomicsCrosstalk between the diseased atherosclerotic aorta and the peripheral nervous system [Adventitia]
The goal of these studies was to delineate mechanisms of crosstalk between the atherosclerotic arterial wall of the aorta and the peripheral nervous system (PNS) in aged hyperlipidemic ApoE-deficient mice. We had observed by immunohistochemistry and morphometry that axon density of the PNS in advent...
ORGANISM(S): Mus musculus 
2022-02-27 | GSE94044 | GEO
UnknownFibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease.
Not available
S-EPMC5065745 | biostudies-literature
UnknownProper restoration of excitation-contraction coupling in the dihydropyridine receptor beta1-null zebrafish relaxed is an exclusive function of the beta1a subunit.
Not available
S-EPMC2613631 | biostudies-literature
UnknownActivation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy.
Not available
S-EPMC4670583 | biostudies-literature
MetabolomicsMechanistic insights into the biological activity of S-Sulfocysteine in CHO cells using a multi-omics approach
S-Sulfocysteine (SSC), a bioavailable L-cysteine derivative (Cys), is known to be taken up and metabolized in Chinese hamster ovary (CHO) cells used to produce novel therapeutic biological entities. To gain a deeper mechanistic insight into the SSC biological activity and metabolization, a multi-omi...
2024-08-08 | MTBLS7424 | MetaboLights
ProteomicsFibroblast Growth Factor (FGF) 23 and FGF Receptor 4 promote cardiac metabolic remodeling in CKD
Frozen mitochondrial pellets were sonicated in SDS followed by centrifugation. 18 micrograms of protein was reduced and alkylated and digested with 1.5 ugs trypsin using an S-Trap micro device (Protifi) and lyophilized. A study pool QC (SPQC) was made from equal volumes of reconstituted samples. 0.7...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-02-14 | MSV000094087 | MassIVE
UnknownX-RAY DENSITOMETRY OF NORWAY SPRUCE SUBFOSSIL WOOD FROM THE AUSTRIAN ALPS.
Not available
S-EPMC4854978 | biostudies-literature
UnknownKlotho Inhibits Interleukin-8 Secretion from Cystic Fibrosis Airway Epithelia.
Not available
S-EPMC5662572 | biostudies-literature
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