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TranscriptomicsWhole genome expression in meningioma
We performed expression profiling of 24 meningioma and two dura controls analyzing 55000 transcripts including 18300 known genes. We compared expression in meningioma vs. dura, expression of low grade (WHO I) vs. higher-grade (WHO II and WHO IIII) tumors and expression of meningothelial and syncytia...
ORGANISM(S): Homo sapiens 
2008-11-20 | E-GEOD-12530 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human meningioma patients undergoing neuro-surgical resection reveals gene expression is associated with Progesterone Receptor Status in Meningioma
Examine gene expression for meningioma cases by hormone receptor status and indicate a stronger association with progesterone than with estrogen receptors Experiment Overall Design: The data are surgical specimens from 31 meningioma patients undergoing neuro-surgical resection at Brigham and Womenâ€...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9438 | biostudies-arrayexpress
ProteomicsProteomic analysis of meningioma of different grades identifies potential therapeutic targets and biomarkers
Meningiomas are common brain tumours arising from meningeal tissue. Despite the majority of them displaying benign features, they can cause mild to severe morbidity. The current main therapeutic approach is complete tumour resection commonly with adjunct radiation therapy. However, tumour location c...
ORGANISM(S): Homo sapiens (Human) 
2019-01-07 | PXD007044 | Pride
Meningioma Lc-ms/ms 
ProteomicsProteomic analysis of meningioma of different grades identifies potential therapeutic targets and biomarkers
Meningiomas are common brain tumours arising from meningeal tissue. Despite the majority of them displaying benign features, they can cause mild to severe morbidity. The current main therapeutic approach is complete tumour resection commonly with adjunct radiation therapy. However, tumour location c...
ORGANISM(S): Homo sapiens (Human) 
2019-01-02 | PXD007073 | Pride
Meningioma Lc-ms/ms 
ProteomicsProteomics pinpoint alterations in grade I meningiomas of male versus female patients
Meningiomas are among the most common primary tumors of the central nervous system (CNS) and originate from the arachnoid or meningothelial cells. Risk factors for the disease include exposure to ionizing radiation, head trauma, and family history. Surgery is the first option of treatment for mening...
ORGANISM(S): Homo sapiens (Human) 
2020-06-30 | PXD015979 | Pride
Grade i meningioma Gender comparison Shotgun proteomics Mass spectrometry 
ProteomicsProteomic analysis of meningioma of different grades identifies potential therapeutic targets and biomarkers
Meningiomas are common brain tumours arising from meningeal tissue. Despite the majority of them displaying benign features, they can cause mild to severe morbidity. The current main therapeutic approach is complete tumour resection commonly with adjunct radiation therapy. However, tumour location c...
ORGANISM(S): Homo sapiens (Human) 
2019-01-02 | PXD007125 | Pride
Proteomics Meningioma 
GenomicsMutational patterns and regulatory networks in epigenetic subgroups of meningioma (H033)
DNA methylation patterns delineate clinically relevant subgroups of meningioma. We previously established the six meningioma methylation classes (MC) benign-1, 2, 3, intermediate-A, B and malignant. Here, we set out to identify subgroup-specific mutational patterns and pathway regulation. Whole-gen...
EGAS00001003481 | EGA
TranscriptomicsHuman primary meningioma vs. non-neoplastic adult meningeal tissue
Meningiomas are common brain tumors that are classified into three World Health Organization grades (Grade I: benign, Grade II: atypical and Grade III: malignant) and are molecularly ill-defined tumors. The purpose of this study was identify microRNA (miRNA) molecular signatures unique to the differ...
ORGANISM(S): Homo sapiens 
2011-01-02 | E-GEOD-19720 | biostudies-arrayexpress
GenomicsHuman WHO grade I sporadic meningiomas
Human WHO grade I sporadic meningiomas: Mutational profiles
PRJEB43143 | ENA
TranscriptomicsWhole genome expression in meningioma
We performed expression profiling of 24 meningioma and two dura controls analyzing 55000 transcripts including 18300 known genes. We compared expression in meningioma vs. dura, expression of low grade (WHO I) vs. higher-grade (WHO II and WHO IIII) tumors and expression of meningothelial and syncytia...
ORGANISM(S): Homo sapiens 
2008-11-21 | GSE12530 | GEO
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