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TranscriptomicsWhole genome expression in meningioma
We performed expression profiling of 24 meningioma and two dura controls analyzing 55000 transcripts including 18300 known genes. We compared expression in meningioma vs. dura, expression of low grade (WHO I) vs. higher-grade (WHO II and WHO IIII) tumors and expression of meningothelial and syncytia...
ORGANISM(S): Homo sapiens 
2008-11-20 | E-GEOD-12530 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human meningioma patients undergoing neuro-surgical resection reveals gene expression is associated with Progesterone Receptor Status in Meningioma
Examine gene expression for meningioma cases by hormone receptor status and indicate a stronger association with progesterone than with estrogen receptors Experiment Overall Design: The data are surgical specimens from 31 meningioma patients undergoing neuro-surgical resection at Brigham and Womenâ€...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9438 | biostudies-arrayexpress
ProteomicsSerum N-glycomics with nanoLC-QToF LC-MS/MS reveals N-glycan biomarkers for glioblastoma, meningioma, and high-grade meningioma
Alteration of glycosylation in cancer cells leaded to the expression of tumor-associated glycans that could be used as a biomarker for diagnosis and prognostic prediction of the diseases. In this study, we used nanoLC-QToF LC-MS/MS for the identification of serum N-glycan biomarkers for detection of...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-03 | MSV000096282 | MassIVE
TranscriptomicsHuman meningioma culture
Comparison of the gene expression profiles with meningiomas of different grading. 24 primary meningioma cultures from surgical specimen were maintained to primary meningioma cultures.
ORGANISM(S): Homo sapiens 
2014-03-06 | E-GEOD-55609 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiles of meningiomas
Meningiomas, one of the most common human brain tumors, are derived from arachnoidal cells associated with brain meninges, usually benign and frequently associated with neurofibromatosis type 2. Here we define a human meningioma-typical miRNA profile and characterize effects of one down-regulated mi...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-17792 | biostudies-arrayexpress
TranscriptomicsMeningiomas tumor recurrence and metabolic aggressiveness expression profile
The aim of this study was to determine the relationship between gene expression profiles and new metabolic subgroups of benign meningioma with potential clinical relevance. 19 human meningiomas biopsies were obtained at the Department of Neurosurgery of the Clinical University Hospital of Valencia. ...
ORGANISM(S): Homo sapiens 
2012-08-31 | E-MEXP-3586 | biostudies-arrayexpress
TranscriptomicsGenomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO.
We report genomic analysis of 300 meningiomas, the most common primary brain tumors, leading to the discovery of mutations in TRAF7, a proapoptotic E3 ubiquitin ligase, in nearly one-fourth of all meningiomas. Mutations in TRAF7 commonly occurred with a recurrent mutation (K409Q) in KLF4, a transcri...
ORGANISM(S): Homo sapiens 
2014-05-29 | E-GEOD-58037 | biostudies-arrayexpress
ProteomicsProteomic analysis of meningioma of different grades identifies potential therapeutic targets and biomarkers
Meningiomas are common brain tumours arising from meningeal tissue. Despite the majority of them displaying benign features, they can cause mild to severe morbidity. The current main therapeutic approach is complete tumour resection commonly with adjunct radiation therapy. However, tumour location c...
ORGANISM(S): Homo sapiens (Human) 
2019-01-07 | PXD007044 | Pride
Meningioma Lc-ms/ms 
ProteomicsIntegrated proteomic, DNA methylation, and targeted Next Generation Sequencing reveals relevant heterogeneity in lower-grade meningioma and a new target in NF2 mutated meningiomas
Meningiomas, the most common primary brain tumours, are classified by the World Health Organization (WHO) into grades 1, 2, and 3. Some grade 1 tumours exhibit increased clinical aggressiveness with the biallelic mutation of Neurofibromatosis 2 (NF2) being the most frequent mutation reported. In our...
ORGANISM(S): Homo sapiens (Human) 
2025-07-02 | PXD058651 | Pride
Brain tumour Ngs Proteomics Meningioma 
ProteomicsProteomic analysis of meningioma of different grades identifies potential therapeutic targets and biomarkers
Meningiomas are common brain tumours arising from meningeal tissue. Despite the majority of them displaying benign features, they can cause mild to severe morbidity. The current main therapeutic approach is complete tumour resection commonly with adjunct radiation therapy. However, tumour location c...
ORGANISM(S): Homo sapiens (Human) 
2019-01-02 | PXD007073 | Pride
Meningioma Lc-ms/ms 
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