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Genomicsba3dbe29-0fd7-4ee5-99b8-d69d3c381e6e - samples
The BAM files for WES and RNA seq used in the article "Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases." on cancer Discovery 2019. PMID: 30787016 PMCID: PMC6497554. Authors : Grant M Fischer, ..., Michael A Davies.
EGAD00001005046 | EGA
TranscriptomicsIdentification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors
We identified the cell cycle-regulated mRNA transcripts genome-wide in the osteosarcoma derived U2OS cell line. This resulted in 2,140 transcripts mapping to 1,871 unique cell cycle-regulated genes that show periodic oscillations across multiple synchronous cell cycles. We identified genomic loci ...
ORGANISM(S): Homo sapiens 
2013-10-11 | E-GEOD-50988 | biostudies-arrayexpress
TranscriptomicsDeep sequencing the circadian transcriptome of Drosophila brain
RNAseq transcriptional profiling of Drosophila brains from wildtype, and period loss-of-function animals with time points taken over two days. 2 days of brain collection, time points at ZT0, ZT6, ZT12, and ZT18; wildtype and per0 flies. 10-12 brains per time point.
ORGANISM(S): Drosophila melanogaster 
2012-01-01 | E-GEOD-29972 | biostudies-arrayexpress
GenomicsIdentification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors [ChIP-seq]
We report the genome wide DNA binding patterns of wild type FOXM1 in asynchronous HeLa cells using chromatin precipitation followed by high-throughput sequencing (ChIP-seq). We find that FOXM1 is bound to the promoter of a number of cell cycle genes including PLK, AURKB, and CCNB1. FOXM1 ChIP-seq i...
ORGANISM(S): Homo sapiens 
2013-11-06 | E-GEOD-52098 | biostudies-arrayexpress
TranscriptomicsDeep sequencing the circadian and light-dependent transcriptome of Drosophila brain
Eukaryotic circadian clocks include transcriptional/translational feedback loops that drive 24-hour rhythms of transcription.These transcriptional rhythms underlie oscillations of protein abundance, thereby mediating circadian rhythms of behavior, physiology, and metabolism. Numerous studies over th...
ORGANISM(S): Drosophila melanogaster 
2012-03-27 | E-GEOD-36108 | biostudies-arrayexpress
TranscriptomicsDifferential expression of genes in the leaves of sugarcane in response to sugar accumulation
In C4 sugarcane (Saccharum spp. hybrids), photosynthetic activity has been shown to be regulated by the demand for carbon from sink tissues. There is evidence, from other plant species, that sink-limitation of photosynthesis is facilitated by sugar-signaling mechanisms in the leaf that affect photo...
ORGANISM(S): Saccharum officinarum 
2008-07-01 | E-GEOD-11934 | biostudies-arrayexpress
GenomicsIdentification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-11-06 | E-GEOD-52100 | biostudies-arrayexpress
UnknownMitochondrial DNA deletions in the cerebrospinal fluid of patients with idiopathic REM sleep behaviour disorder.
Not available
S-EPMC10963194 | biostudies-literature
GenomicsLive cell monitoring of periodic gene expression in synchronous human cells identifies forkhead genes involved in cell cycle control
We report the genome wide DNA binding patterns of wild type FOXK1 in asynchronous HeLa cells using chromatin precipitation followed by high-throughput sequencing (ChIP-seq). We find that FOXK1 is bound to the promoter of a number of cell cycle genes including the E2F binding partner TFDP1. This st...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-GEOD-39138 | biostudies-arrayexpress
UnknownSmall cell and non small cell lung cancer form metastasis on cellular 4D lung model.
Not available
S-EPMC5907356 | biostudies-literature
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