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ProteomicsA wide-proteome analysis to identify molecular pathways in-volved in kidney response to high fat diet in mice
The etiopathogenesis of obesity-related chronic kidney disease (CKD) is still scarcely understood. Aim of this study is to shed light on the molecular pathogenesis of obesity-induced CKD by assessing the effect of high fat diet (HF) on molecular pathways leading to organ damage, steatosis, and fibro...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD031915 | Pride
Proteomics  nanolc-ms/ms 
Proteomicsthe expression of BDNF and the levels of this neurotrophin influence the behavioural response in Zebrafish
Experimental evidence suggests that environmental stress conditions can alter the expression of BDNF and the levels of this neurotrophin influence the behavioural response in mammalian models. Recently it has been demonstrated that the exposure to 34° C for 21 days alters the brain proteome and beha...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2022-06-09 | PXD030733 | Pride
Proteomics Nano lc-ms/ms 
ProteomicsA multi¬omic analysis reveal gender differences in the hippocampus of Alzheimer disease subjects
Alzheimer’s disease (AD) is the most common neurodegenerative pathology affecting more than 20 million people worldwide and the leading cause of dementia. Although AD neuropathology has been well defined, the underlying causes of the disease remain debatable. Recently, sex and gender are emerging as...
ORGANISM(S): Homo sapiens (Human) 
2024-10-01 | PXD034137 | Pride
Proteomics Nanolc-ms/ms 
ProteomicsPeptidomic changes in the milk of water buffaloes (Bubalus bubalis) with intramammary infection by non-aureus staphylococci
Infectious mastitis by non-aureus staphylococci (NAS) is a significant issue in dairy buffalo farming. In a herd with subclinical NAS mastitis, we identified Staphylococcus microti as the predominant species by MALDI-TOF mass spectrometry. To assess milk protein integrity and investigate potential d...
ORGANISM(S): Bubalus bubalis 
2022-06-09 | PXD028793 | Pride
Nano-lc-ms/ms 
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