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ProteomicsMHCquant2 refines immunopeptidomics tumor antigen discovery
The identification of human leukocyte antigen (HLA)-presented peptides as targets of anti-cancer T cell response is pivotal for the development of novel immunotherapies. Mass spectrometry (MS)-based immunopeptidomics enables the detection of these peptides, yet confident identifications and thus imp...
ORGANISM(S): Homo sapiens (Human) 
2025-08-22 | PXD058436 | Pride
Immunopeptidomics Nf-core Mhcquant Pipeline Dda 
ProteomicsPhase I study of immunopeptidome-guided personalized multi-peptide vaccines in chronic lymphocytic leukemia patients under BTK-inhibitor-based regimes
Cancer peptide vaccines hold promise as therapeutic approach, but their effectiveness has been hampered by lack of suitable antigens and the variability of HLA backgrounds among patients, which restricts their applicability.. We here introduce a novel warehouse concept for the construction of person...
ORGANISM(S): Homo sapiens (Human) 
2026-01-22 | PXD059004 | Pride
Human Cll Immunopeptidomics Lc-ms/ms 
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