Proctor2008 - p53/Mdm2 circuit - p53 stabilisation by ATM
This model is described in the article:
Explaining oscillations and
variability in the p53-Mdm2 system.
Proctor CJ, Gray DA.
BMC Syst Biol 2008; 2: 75
Abstract:
BACKGROUND: In individual living cells p53 has been...
Proctor2008 - p53/Mdm2 circuit - p53 stabilisation by p14ARF
This model is described in the article:
Explaining oscillations and
variability in the p53-Mdm2 system.
Proctor CJ, Gray DA.
BMC Syst Biol 2008; 2: 75
Abstract:
BACKGROUND: In individual living cells p53 has b...
This a model from the article:
Experimental and computational analysis of polyglutamine-mediated cytotoxicity.
Tang MY, Proctor CJ, Woulfe J, Gray DA.
PLoS Comput Biol.2010 Sep 23;6(9).
20885783,
Abstract:
Expanded polyglutamine (polyQ) p...
Proctor2013 - Effect of Aβ immunisation
in Alzheimer's disease (stochastic version)
Extension of a previously published
stochastic model (designed to examine some of the key pathways
involved in the aggregation of amyloid-beta (A
β) and
the micro-tubular binding protein tau (
BIOMD0000000286,
BIOMD...
Proctor2013 - Effect of Aβ immunisation
in Alzheimer's disease (deterministic version)
Extension of a previously published stochastic model (designed
to examine some of the key pathways involved in the aggregation
of amyloid-beta (Aβ) and the micro-tubular binding protein
tau (
BIOMD00000...
Proctor2007 - Age related decline of proteolysis, ubiquitin-proteome system
This
is a stochastic model of the ubiquitin-proteasome system for a
generic pool of native proteins (NatP), which have a half-life of
about 10 hours under normal conditions. It is assumed that these
...
