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UnknownDeep gray matter volume loss drives disability worsening in multiple sclerosis.
Not available
S-EPMC5838522 | biostudies-literature
UnknownRandomized international phase III trial of ERCC1 and RRM1 expression-based chemotherapy versus gemcitabine/carboplatin in advanced non-small-cell lung cancer.
Not available
S-EPMC3691357 | biostudies-literature
ProteomicsDistinct branches of the N-end rule pathway modulate the plant immune response
The N-end rule pathway is a highly conserved constituent of the ubiquitin proteasome system, though little information exists regarding biological roles. Here we show that the cysteine (Cys-) and glutamine (Gln)-specific amino-terminal (Nt)-amidase NTAQ1 branches are both components of the plant imm...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-11-06 | PXD008520 | Pride
Ntaq N-end rule pathway Plant immunity Erfvii Amino-terminal glutamine amidase 
ProteomicsMutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity
The colony-stimulating factor 3 receptor (CSF3R) controls the growth of neutrophils, the most abundant type of white blood cell. In healthy neutrophils, signaling is dependent on CSF3R binding to its ligand, CSF3. A single amino acid mutation in CSF3R, T618I, instead allows for constitutive, ligand-...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD035664 | Pride
Receptor Mutagenesis Neutrophil Glycoprotein 
UnknownUsing global team science to identify genetic parkinson's disease worldwide.
Not available
S-EPMC7410260 | biostudies-literature
TranscriptomicsSex-dependent RNA expression in opossum brain and liver.
To compensate for the increased dosage of X chromosomes in females one of the two X chromosomes is inactivated in eutherian mammals in an Xist-dependent manner. Xist is, however, not found in metatherians. Here we describe long non-coding RNA Rsx (RNA-on-the-silent X) that exhibits properties consis...
ORGANISM(S): Monodelphis domestica 
2012-06-11 | E-GEOD-36861 | biostudies-arrayexpress
MetabolomicsAlignment of multiple metabolomics LC-MS datasets from disparate diseases to reveal fever-associated metabolites

Acute febrile illnesses are still a major cause of mortality and morbidity globally, particularly in low to middle income countries. The aim of this study was to determine any possible metabolic commonalities of patients infected with disparate pathogens that cause fever. Three liquid chromatogra...

2023-07-17 | MTBLS4895 | MetaboLights
UnknownHIV Type 1 Disease Progression to AIDS and Death in a Rural Ugandan Cohort Is Primarily Dependent on Viral Load Despite Variable Subtype and T-Cell Immune Activation Levels.
Not available
S-EPMC4425824 | biostudies-literature
UnknownDisease modification and biomarker development in Parkinson disease: Revision or reconstruction?
Not available
S-EPMC7220234 | biostudies-literature
TranscriptomicsGene expression data from primate postnatal brain development - superior frontal gyrus
In development, timing is of the utmost importance, and the timing of various developmental processes are often changed during evolution. During human evolution sexual maturation has been delayed relative to other primates and this may have played a critical role for both the increase of human brain...
ORGANISM(S): Homo sapiens 
2009-03-09 | E-GEOD-15163 | biostudies-arrayexpress
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