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MetabolomicsOral-gut microbiome and plasma metabolome reveal incremental restratification of coronary artery disease from the clinical gray zone
Clinical prediction models have been widely applied for risk stratification of coronary artery disease (CAD), yet approximately 20% to 40% of screened individuals fall into the intermediate-risk interval and face a decision gap. Here, we adopted a two-stage validation design. In the first stage, a c...
2026-08-31 | MTBLS15425 | MetaboLights
TranscriptomicsTranscription profiling of human post mortem spinal cord grey matter from sporadic and familial ALS patients vs controls to identify amyotrophic lateral sclerosis (ALS) associated genes
Identification of amyotrophic lateral sclerosis (ALS) associated genes. Post mortem spinal cord grey matter from sporadic and familial ALS patients compared with controls.
ORGANISM(S): Homo sapiens 
2007-09-26 | E-GEOD-833 | biostudies-arrayexpress
TranscriptomicsPervasive effects of aging on gene expression in wild wolves
We sequenced total RNA from whole blood samples of 27 wild gray wolves from Yellowstone National Park. Gene expression level analysis of both male and female wolves, ranging from ages 0.8-8.8 years.
ORGANISM(S): Canis lupus 
2016-07-27 | E-GEOD-80440 | biostudies-arrayexpress
ProteomicsNeutrophil specific granule and NETosis defect in Gray Platelet Syndrome
Gray Platelet Syndrome (GPS) is an autosomal recessive bleeding disorder characterized by a lack of α-granules in platelets and progressive myelofibrosis. Rare loss of function variants in NBEAL2, a member of the family of BEACH genes, are causal of GPS. The gene is involved in fusion, fission and t...
ORGANISM(S): Homo sapiens (Human) 
2021-01-28 | PXD017784 | Pride
Neutrophil Gray platelet syndrome 
MetabolomicsDIVA Metabolomics: Differentiating Vaccination Status Following Viral Challenge Using Metabolomic Profiles
This study employed metabolomic profiling technologies, to identify metabolites (small molecules) in blood which are found at different levels in vaccinated compared to non-vaccinated animals exposed to virus.
2018-07-13 | MTBLS456 | MetaboLights
TranscriptomicsMicroarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer’s disease
Alzheimer's disease (AD) is a devastating neurodegenerative disorder that threatens to reach epidemic proportions as our population ages. Although much research has examined molecular pathways associated with AD, relatively few studies have focused on critical early stages. Our prior microarray stud...
ORGANISM(S): Homo sapiens 
2011-07-31 | E-GEOD-28146 | biostudies-arrayexpress
UnknownLocalization of genes for V+LDL plasma cholesterol levels on two diets in the opossum Monodelphis domestica.
Not available
S-EPMC2936748 | biostudies-literature
UnknownUSMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis.
Not available
S-EPMC6140788 | biostudies-literature
UnknownPalmitoylation of the pore-forming subunit of Ca(v)1.2 controls channel voltage sensitivity and calcium transients in cardiac myocytes.
Not available
S-EPMC9963536 | biostudies-literature
UnknownOral vaccination of wildlife using a vaccinia-rabies-glycoprotein recombinant virus vaccine (RABORAL V-RG®): a global review.
Not available
S-EPMC5610451 | biostudies-literature
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