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TranscriptomicsProstaglandin E2 regulates B cell proliferation through a candidate tumor suppressor, Ptger4
Recognition of foreign antigens by B cell receptor (BCR) on mature B cells leads to their clonal expansion, which is critically important for the effective host defence of the organism. However, excessive antigenic responses or reaction of B cells against body’s own components frequently lead to d...
ORGANISM(S): Mus musculus 
2008-12-14 | E-GEOD-9847 | biostudies-arrayexpress
UnknownEnzyme-Activated, Chemiluminescent Siderophore-Dioxetane Probes Enable the Selective and Highly Sensitive Detection of Bacterial Pathogens.
Not available
S-EPMC9322335 | biostudies-literature
UnknownDevelopment of an IgG-Fc fusion COVID-19 subunit vaccine, AKS-452.
Not available
S-EPMC8491978 | biostudies-literature
TranscriptomicsGenetic alteration in recurrent melanoma
It is generally accepted that human cancers derive from a mutated single cell. However, the genetic steps characterizing various stages of progression remain unclear. Studying a unique case of metastatic melanoma, we observed that cell lines derived from metachronous metastases arising over a decade...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-8777 | biostudies-arrayexpress
TranscriptomicsRNA-seq performed on Brassica oleracea var. italica (broccoli) control and blindness-affected plants, sampled from both leaves and roots.
Blindness, characterized by apical abortion, is a physiological condition that affects the Brassica family. While exposure to low temperatures during early development has been associated with blindness, the underlying causes and their impact on proper development remain unknown. This study aims to ...
ORGANISM(S): Brassica oleracea var. italica 
2023-07-18 | E-MTAB-13076 | biostudies-arrayexpress
TranscriptomicsTargeting IRAK1 as a therapeutic approach for Myelodysplastic Syndrome
Myelodysplastic Syndromes (MDS) result from expansion of defective hematopoietic stem/progenitor clones. There is an urgent need to develop targeted therapies capable of eliminating the defective MDS clones. We identified that IRAK1, an immune modulating kinase, is overexpressed and hyperactivated i...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-46346 | biostudies-arrayexpress
UnknownMonth-6 primary outcomes of the READ-3 study (Ranibizumab for Edema of the mAcula in Diabetes-Protocol 3 with high dose).
Not available
S-EPMC5129796 | biostudies-literature
UnknownAdd-On Treatment With Zilebesiran for Inadequately Controlled Hypertension: The KARDIA-2 Randomized Clinical Trial.
Not available
S-EPMC12120674 | biostudies-literature
TranscriptomicsCIT_VADS_BW_OMICS
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net); Integrative study based on 89 patients with Head and Neck Squamous Cell Carcinoma (HNSCC); 89 Affymetrix HG-U133 Plus 2.0 GeneChips arrays; 88 samples on HumanCNV370-Quad Ge...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-MTAB-1328 | biostudies-arrayexpress
UnknownMapping copy number variation by population-scale genome sequencing.
Not available
S-EPMC3077050 | biostudies-literature
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