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MetabolomicsThe Green Tea Modulates Large Intestinal Microbiome and Exo/Endogenous Metabolome altered through Chronic UVB-exposure (Endogenous assays)
The attenuating effects of green tea supplements (GTS) against the ultraviolet (UV) radiation induced skin damages are distinguished. However, the concomitant effects of GTS on the large intestinal microbiomes and associated metabolomes are largely unclear. Herein, we performed an integrated microbi...
2018-09-14 | MTBLS527 | MetaboLights
MetabolomicsComprehensive lipid analysis of green Arabica coffee beans by LC-HRMS/MS
Lipids play an important role in coffee bean development, coffee brew and in the effects of coffee on human health. They account for around 17% of the dry bean weight and encompass different classes and subclasses, mostly triacylglycerols (TAG) and a minor quantity of phospholipids (PL) and βN-alkan...
2021-11-19 | MTBLS1972 | MetaboLights
TranscriptomicsSystem responses to equal doses of photosynthetically usable radiation of blue, green, and red light in the marine diatom Phaeodactylum tricornutum.
We have studied the transcriptional, metabolic and photo-physiological responses to light of different spectral quality in the marine diatom Phaeodactylum tricornutum through time-series studies of cultures exposed to equal doses of photosynthetically usable radiation of blue, green and red light. T...
ORGANISM(S): Phaeodactylum tricornutum 
2014-12-22 | E-GEOD-55959 | biostudies-arrayexpress
MetabolomicsExtracellular Vesicles from probiotics mediated Walnut green husk polysaccharide alleviates ochratoxin-A-induced cognitive impairment via SCFA and 5-HT mediated microbiota-gut-brain axis

BACKGROUND: Ochratoxin A (OTA) have made it a serious hazard to food safety worldwide that poses a serious health risk to humans. Our previous research showed that Walnut green husk polysaccharides (WGP) can effectively alleviate intestinal inflammation and intestinal microbiota ...

2024-10-10 | MTBLS10673 | MetaboLights
TranscriptomicsIdentification of target genes regulated by M-NM-^TNp63M-NM-1 in SaOS-2 cells stably expressed with M-NM-^TNp63M-NM-1
To identify the target gene of M-NM-^TNp63M-NM-1, in osteosarcoma cells, we performed the global gene expression profiling in SaOS- 2 cells stably overexpressing the M-NM-^TNp63M-NM-1 gene (SaOS- 2-M-NM-^TNp63M-NM-1). M-NM-^TNp63M-NM-1 target genes were identified by comparison with genes expressed...
ORGANISM(S): Homo sapiens 
2014-02-27 | E-GEOD-54942 | biostudies-arrayexpress
TranscriptomicsExpression analysis of African Green Monkeys after treatment with a miR-33a/b-targeting LNA-antimiR
Investigation of whole genome gene expression level changes in African Green Monkeys treated with antimiR-33a/b, compared to the animal treated with vehicle The treatment of the monkeys is further described in Rottiers V, Obad S, McGarrah R, Black JC, Lindholm M, Goody R, Lawrence M, Whetstine JR, G...
ORGANISM(S): Chlorocebus aethiops 
2013-08-23 | E-GEOD-50116 | biostudies-arrayexpress
TranscriptomicsMitochondrial two-component signaling systems in Candida albicans
Two-component signal transduction pathways are one of the primary means by which microorganisms respond to environmental signals. These signaling cascades originated in prokaryotes and were inherited by eukaryotes via endosymbiotic lateral gene transfer from ancestral cyanobacteria. We report here t...
ORGANISM(S): Candida albicans 
2013-07-02 | E-GEOD-45438 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of ATCC46645 strain and isogenic M-NM-^TpacC Aspergillus fumigatus mutant during murine infection
In lung diseases caused by the major mould pathogen Aspergillus fumigatus the pulmonary epithelium is destroyed by invasive growth of fungal hyphae, a process thought to require fungal proteases. Here we show that the A. fumigatus pH-responsive transcription factor PacC governs expression of secrete...
ORGANISM(S): Aspergillus fumigatus 
2014-10-20 | E-GEOD-54810 | biostudies-arrayexpress
TranscriptomicsGene expression in an EMT model using an immortalized bronchial epithelial cell line induced by TGF-M-NM-21
This study aimed to establish an epithelial-mesenchymal transition (EMT) model with an immortalized human bronchial epithelial cell line, M-BE, and to identify an EMT signature gene set. The TGF-M-NM-21-induced M-BE cells got spindle-shaped fibroblast-like morphology and lost the cell-cell contact, ...
ORGANISM(S): Homo sapiens 
2013-10-06 | E-GEOD-40374 | biostudies-arrayexpress
TranscriptomicsWnt signaling involved in mouse myoblast differentiation
Wnt/M-NM-2-catenin signaling is involved in various aspects of skeletal muscle development and regeneration. In addition, Wnt3a and M-NM-2-catenin are required for muscle-specific gene transcription in embryonic carcinoma cells and satellite-cell proliferation during adult skeletal muscle regenerati...
ORGANISM(S): Mus musculus 
2011-07-15 | E-GEOD-30077 | biostudies-arrayexpress
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