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TranscriptomicsGene expression data from hippocampus, striatum, hypothalamus cortex, Drd2-MSNs and Drd1-MSNs in mice
Goal of the experiment: Analysis of gene expression changes in the cortex, striatum, hippocampus, hypothalamus, Drd2-MSNs and Drd1-MSNs of mice with a postnatal, neuron-specific ablation of GLP or G9a as compared to control mice. For microarray analysis, hippocampus, hypothalamus, cortex and striatu...
ORGANISM(S): Mus musculus 
2009-12-10 | E-GEOD-19402 | biostudies-arrayexpress
ModelsMusante2017 - Switching behaviour of PP2A inhibition by ARPP-16 - mutual inhibitions and PKA inhibits MAST3 and dominant negative effect
Musante2017 - Switching behaviour of PP2A inhibition by ARPP-16 - mutual inhibitions and PKA inhibits MAST3 and dominant negative effect This model is described in the article: Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein pho...
2024-09-02 | BIOMD0000000645 | BioModels
ModelsMusante2017 - Switching behaviour of PP2A inhibition by ARPP-16 - mutual inhibitions
Musante2017 - Switching behaviour of PP2A inhibition by ARPP-16 - mutual inhibitions This model is described in the article: Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition. Musante V, Li L, Kanyo ...
2024-09-02 | BIOMD0000000643 | BioModels
ModelsMusante2017 - Switching behaviour of PP2A inhibition by ARPP-16 - mutual inhibitions and PKA inhibits MAST3
Musante2017 - Switching behaviour of PP2A inhibition by ARPP-16 - mutual inhibitions and PKA inhibits MAST3 This model is described in the article: Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition. ...
2024-09-02 | BIOMD0000000644 | BioModels
TranscriptomicsComparative analysis of Drd1+ Medium Spiny Neurons, Drd2+ Medium Spiny Neurons, Motor Neurons, and Purkinje Neurons
The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations. Using Bacterial Artificial Chromosome (BAC) transgenic mice which express EGFP-tagged ribosomal protein L10a in defined cell populations, we have developed a methodology...
ORGANISM(S): Mus musculus 
2008-11-14 | E-GEOD-13387 | biostudies-arrayexpress
TranscriptomicsComparative analysis of Drd1+ Medium Spiny Neurons and Drd2+ Medium Spiny Neurons
The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations. Using Bacterial Artificial Chromosome (BAC) transgenic mice which express EGFP-tagged ribosomal protein L10a in defined cell populations, we have developed a methodology...
ORGANISM(S): Mus musculus 
2008-11-14 | E-GEOD-13384 | biostudies-arrayexpress
TranscriptomicsComparative analysis of Drd1+ Medium Spiny Neurons, Drd2+ Medium Spiny Neurons, cocaine treatment
The cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations. Using Bacterial Artificial Chromosome (BAC) transgenic mice which express EGFP-tagged ribosomal protein L10a in defined cell populations, we have developed a methodology...
ORGANISM(S): Mus musculus 
2008-11-14 | E-GEOD-13386 | biostudies-arrayexpress
UnknownRegulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum.
Not available
S-EPMC544317 | biostudies-literature
TranscriptomicsApplication of a translational profiling approach for the comparative analysis of CNS cell types.
Comparative analysis can provide important insights into complex biological systems. As demonstrated in the accompanying paper, Translating Ribosome Affinity Purification (TRAP), permits comprehensive studies of translated mRNAs in genetically defined cell populations following physiological perturb...
ORGANISM(S): Mus musculus 
2008-11-14 | E-GEOD-13379 | biostudies-arrayexpress
TranscriptomicsEffect of fluoxetine treatment on translational profiles of S100a10 cortical pyramidal cells
Molecular phenotyping of cell types and neural circuits underlying pathological neuropsychiatric conditions and their responses to therapy provides one avenue for the development of more specific and effective treatments. In this study, we identify a cell population in the cerebral cortex that shows...
ORGANISM(S): Mus musculus 
2012-05-31 | E-GEOD-35761 | biostudies-arrayexpress
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