Sort   by:  
 Page size 
ProteomicsHsPlasma_LMF
Human low-molecular weight (
ORGANISM(S): Homo Sapiens (human) 
2010-12-31 | PAe004835 | PeptideAtlas
ProteomicsInvadopodia small extracellular vesicles glioblastoma
The therapeutic efficacy of radiotherapy and chemotherapy with temozolomide (TMZ) for glioblastoma (GBM) is currently limited by the augmented invasive abilities of GBM cells that survive treatment, however the underlying mechanisms remain poorly understood. Due to their ability of transporting onco...
ORGANISM(S): Homo sapiens (Human) 
2023-07-24 | PXD031077 | Pride
Therapeutic Glioblastoma Cancer Small extracellular vesicles Invadopodia Radiotherapy 
ProteomicsHeart surfaceome profiling using biotin capture
Cell surface proteins (surfaceome) represent key signalling and interaction molecules for therapeutic targeting, biomarker profiling, and cellular phenotyping. Understanding the surfaceome of complex tissues including the heart is essential to investigate membrane composition and function in physiol...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000095912 | MassIVE
ProteomicsRapid and in-depth proteomic profiling of small extracellular vesicles for ultralow samples
The form and function of extracellular vesicles (EV) is defined by their proteome. This knowledge is essential to describe and understand EVs, encompassing their marker proteins, capacity as a signalling platform, and utility as diagnostic tools and therapeutic targets. However, EV are low-abundant ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-16 | MSV000092668 | MassIVE
Proteomicsintercardiac Phosphoproteome/proteome regulation of cardiomyocyte-fibroblast signaling
Secretome-mediated signaling from human iPSC-derived cardiomyocytes (TGF-beta induced dysfunction) to primary human cardiac fibroblasts was investigated to identify downstream regulators of fibrosis. Quantitative proteomic profiling revealed a dynamic reprogramming of fibroblast global proteome, wit...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-06-27 | MSV000092293 | MassIVE
ProteomicsExtracellular matrix proteome remodeling with substrate stiffness
Extracellular matrix proteomic profiling Mass spectrometry characterization illustrated a reprogrammed proteome in response to matrix stiffness, including a core subset of 84 ECM-specific proteins, including various ECM regulators and tissue-associated ECM-related proteins. Further, we observe remod...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000092971 | MassIVE
ProteomicsMultiomic analysis of PI3K in Atrial Myopathy
Here, we undertook comprehensive physiological and molecular analyses in cardiac-specific transgenic mice with increased or decreased PI3K to assess the dose response impact of directly regulating PI3K. Elevated PI3K was associated with a dose-dependent increase in heart size, and preserved/enhanced...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000092855 | MassIVE
UnknownIdentification of six new susceptibility loci for invasive epithelial ovarian cancer.
Not available
S-EPMC4445140 | biostudies-literature
Sort   by:  
 Page size