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UnknownMicroutrophin delivery through rAAV6 increases lifespan and improves muscle function in dystrophic dystrophin/utrophin-deficient mice.
Not available
S-EPMC2643133 | biostudies-literature
UnknownrAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.
Not available
S-EPMC4244883 | biostudies-literature
ProteomicsSite-specific identification of UFMylation by remnant VG-immunoprecipitation
Site specific proteomic identification of UFMylation sites: i) Comparision of antibody clones, ii) comparision of mouse tissues, iii) quantification in human skeletal muscle biopsies from ALS participants and controls
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-03-28 | PXD051412 | Pride
Ufm1 Ufmylation 
TranscriptomicsHistone deacetylase inhibition replicates aspects of the adaptive response to exercise and improves muscle metabolism and cardiac function in obesity.
Drugs used to treat obesity and type 2 diabetes have limited efficacy in directly normalising muscle metabolism. The discovery of molecules mediating exercise adaptations, and drugs that modulate their activity, is a potential strategy to address this therapeutic gap. Here we show that genetic impai...
ORGANISM(S): Mus musculus 
2015-01-28 | E-GEOD-54642 | biostudies-arrayexpress
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