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TranscriptomicsMethod Study
High-throughput sequencing (HTS) of antibody amplicon libraries has become a powerful method in the emerging field of systems immunology. However, numerous sources of bias in HTS workflows may affect antibody repertoire data. A crucial step in antibody amplicon library preparation is the addition of...
ORGANISM(S): Mus musculus 
2014-02-20 | E-MTAB-2226 | biostudies-arrayexpress
TranscriptomicsUSR_template_replicates
Next-generation sequencing (NGS) of antibody variable regions has emerged as a powerful tool in systems immunology by providing quantitative molecular information on polyclonal humoral immune responses. Reproducible and robust information on antibody repertoires is valuable for basic and applied imm...
ORGANISM(S): Mus musculus 
2013-10-26 | E-MTAB-1896 | biostudies-arrayexpress
ProteomicsBenchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling
Antibodies are immune glycoproteins that represent a crucial part of the adaptive immune system as they mediate broad protection against viruses, bacteria, and cancer. Moreover, antibodies may serve as a unique source of information on past and current physiological and pathological events in the hu...
ORGANISM(S): Homo sapiens (Human) 
2024-06-04 | PXD046237 | Pride
Human Lc-msms Plasma Antibody 
TranscriptomicsSingle-cell immune repertoire sequencing of bone marrow plasma cells following infection and immunizations
We performed single-cell transcriptome and antibody repertoire sequencing of bone marrow plasma cells following protein (OVA and TNFR2) immunizations or infection with high dose LCMV clone 13.
ORGANISM(S): Mus musculus 
2021-12-01 | E-MTAB-11096 | biostudies-arrayexpress
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