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MetabolomicsSubcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages
Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, remains the world's deadliest infectious disease. Sterilizing chemotherapy requires at least 6 months of multidrug therapy. Difficulty visualizing the subcellular localization of antibiotics in infected host cells means t...
2020-12-07 | MTBLS959 | MetaboLights
TranscriptomicsmiR-155 regulates the ability of circulating cancer cells to colonize and establish metastasis
Abstract: Metastases are established through a complex multistep process by which tumor cells disseminate from the primary tumor and expand at distant sites. Traditionally, studies on metastasis have focused on proteins and protein-coding genes, but recently microRNAs (miRNAs) have achieved increasi...
ORGANISM(S): Homo sapiens 
2012-05-02 | E-GEOD-37719 | biostudies-arrayexpress
UnknownTracking Ovine Pulmonary Adenocarcinoma Development Using an Experimental Jaagsiekte Sheep Retrovirus Infection Model
Not available
S-EPMC11353984 | biostudies-literature
UnknownChemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial.
Not available
S-EPMC3109515 | biostudies-literature
GenomicsEGAS00001000462-sc-20170511 - samples
The offspring of first cousin marriages have ~6% of their genome autozygous, i.e. homozygous identical by descent, or even more if there was further consanguinity in their ancestry. In the UK there are large populations with very high first cousin marriage rates of 20-50%. Sequencing the exomes of...
EGAD00001003329 | EGA
GenomicsEGAS00001000462-sc-20141120 - samples
The offspring of first cousin marriages have ~6% of their genome autozygous, i.e. homozygous identical by descent, or even more if there was further consanguinity in their ancestry. In the UK there are large populations with very high first cousin marriage rates of 20-50%. Sequencing the exomes of...
EGAD00001001079 | EGA
GenomicsAutozygosity pilot Born in Bradford
The offspring of first cousin marriages have ~6% of their genome autozygous, i.e. homozygous identical by descent, or even more if there was further consanguinity in their ancestry. In the UK there are large populations with very high first cousin marriage rates of 20-50%. Sequencing the exomes of...
EGAS00001000462 | EGA
TranscriptomicsGenetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predispose to myeloproliferative neoplasms
Genome-wide association study of JAK2 V617F negative myeloproliferative neoplasms consisting of 524 cases at stage 1
ORGANISM(S): Homo sapiens 
2015-02-20 | E-MTAB-3340 | biostudies-arrayexpress
TranscriptomicsCD34 negative populations are associated with an increased relapse risk in childhood AML and harbor chemo-resistant leukemia stem cells
Differences in chemo-sensitivity of subpopulations of AML stem cells could have important clinical implications. Using in vitro cytotoxicity, xenograft models and colony forming assays, we compared chemotherapy sensitivity between Lineage (Lin-)CD34-CD38-, Lin-CD34-CD38+, Lin-CD34+CD38- and Lin-CD34...
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-45249 | biostudies-arrayexpress
UnknownFavorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of COVID-19.
Not available
S-EPMC11327787 | biostudies-literature
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