Sort   by:  
 Page size 
UnknownA course with a difference. Fighting infectious diseases with technology and knowledge-transfer.
Not available
S-EPMC1796770 | biostudies-literature
TranscriptomicsInflammatory gene expression in response to sub-lethal ricin exposure in Balb/c mice
The toxin ricin has been shown to cause inflammatory lung damage, leading to pulmonary oedema and, at higher doses, mortality. In order to understand the genetic basis of this inflammatory cascade a custom microarray platform (1509 genes) directed towards immune and inflammatory markers was used to ...
ORGANISM(S): Mus musculus 
2009-08-19 | E-GEOD-17431 | biostudies-arrayexpress
TranscriptomicsMycobacteria-Dependent Expression of microRNA-142-3p Reduces WASP Family Proteins and Controls Phagocytosis
Phagocytosis requires the activation of a plethora of mechanisms that include the activation of the actin cytoskeleton guided by the Arp2/3 complex. These are promoted by activators such as the Wiskott Aldrich Syndrome Protein (WASP) family members. In order to further understand the molecular mecha...
ORGANISM(S): Mus musculus 
2013-06-16 | E-GEOD-23429 | biostudies-arrayexpress
TranscriptomicsInflammatory gene expression in response to sublethal phosgene exposure in Balb/c mice
Phosgene is a lung damaging chemical warfare agent which can cause death by the inhalation route. In this study the inflammatory response to phosgene was mapped over a 96h time-course using a custom microarray in the Balb/c mouse. Three groups of six mice were exposed to phosgene and a three groups ...
ORGANISM(S): Mus musculus 
2011-03-01 | E-GEOD-17249 | biostudies-arrayexpress
TranscriptomicsInflammatory gene expression in response to Francisella tularensis exposure in Balb/c mice
Francisella tularensis may enter the body thorugh the lungs and cause fatal infection. In this study the inflammatory response to the virulent strain of Francisella (Schu4) was mapped over a 96h time-course using a custom microarray. Six groups of 4 mice were exposed to aerosolised Francisella tular...
ORGANISM(S): Mus musculus 
2011-03-01 | E-GEOD-17248 | biostudies-arrayexpress
TranscriptomicsEffect of Pro- and anti-inflammatory lipids in intracellular survival and killing of mycobacteria
Mouse macrophages J774A.1 were pre-treated with the anti-inflammatory lipid eicosapenaenoic acid (EPA) or the pro-inflammatory lipid ceramide (Cer) for 3h. Macrophages were then infected with Mycobacterium smegmatis for 1h, and total RNA was collected. In a parallel experiment, infected macrophages ...
ORGANISM(S): Mus musculus 
2015-01-20 | E-GEOD-27277 | biostudies-arrayexpress
Sort   by:  
 Page size