Growth differentiation factor 15 (gdf15)

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Unknown (333)
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biostudies-arrayexpress (268)
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Mass Spectrometry (9)
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HPC (1)
10x chromium (1)
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Axon Instruments GenePix 4000B scanner (1)
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2010 (54)
2011 (42)
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2014 (33)
2012 (27)
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2015 (18)
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2008 (6)
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2016 (5)
2007 (5)
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CHEBI ID

CHEBI:49300 (1)
CHEBI:49299 (1)
CHEBI:49298 (1)
CHEBI:16243 (1)
CHEBI:8113 (1)
CHEBI:27881 (1)
CHEBI:17558 (1)
CHEBI:68352 (1)
CHEBI:67486 (1)
CHEBI:27475 (1)
CHEBI:15600 (1)
CHEBI:90 (1)

Metabolite Name

Beta-Nicotinamide adenine dinucleotide phosphate (NADP) (1)
Guanosine diphosphate (GDP) (1)
Adenosine-5'-triphosphate (ATP) (1)
Adenosine-5'-diphosphate (ADP) (1)
Beta-Nicotinamide adenine dinucleotide (NAD) (1)
Thymideine-monophosphate (dTMP) (1)
Adenosine-3',5'-cyclic monophosphate (cAMP) (1)
1,4-Dihydronicotinamide adenine dinucleotide (NADH) (1)
UDP-Glucuronate (1)
N-Acetylglucosamine 6-phosphate (1)
2-Hydroxybutanoic acid (1)
N-formyl-L-methionine (1)
Guanosine monophosphate (GMP) (1)
Hydroxypropionic acid (1)
Cis-Aconitate (1)
2-Hydroxyglutarate (1)
N-Acetylglucosamine 1-phosphate (1)
Gamma-Aminobutyric acid (1)
S-Adenosylmethionine (1)
3-Phosphoglycerate (1)
6-Phosphogluconate (1)
UDP-N-acetylglucosamine (1)
Malate (1)
Histidine (1)
Oxidized glutathione (1)
Glucosamine 6-phosphate (1)
Glutamate (1)
Leucine (1)
Aspartate (1)
2-Ketobutyric acid (1)

First Public Date

2026 (7)
2024 (5)
2014 (5)
2023 (4)
2022 (3)
2025 (2)
2019 (1)
2017 (1)

Modification

2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (139)
ChIP-chip by tiling array (27)
ChIP-seq (26)
RNA-seq of coding RNA (13)
Other (7)
Methylation profiling by array (7)
Single nucleus RNA sequencing (6)
RNA-seq of coding RNA from single cells (6)
Transcription profiling by tiling array (5)
Transcription profiling by RT-PCR (5)
Spatial transcriptomics by high-throughput sequencing (4)
ChIP-chip by array (3)
Comparative genomic hybridization by array (3)
Methylation profiling by high throughput sequencing (3)
RNA-seq of non coding RNA (3)
Unknown experiment type (2)
ScATAC-seq (2)
MicroRNA profiling by array (2)
Human - Single-cell sequencing (1)
Cell line - One-color microarray (1)
ATAC-seq (1)
DNA-seq (1)
Proteomic profiling by array (1)

Release Date

2025 (79)
2024 (54)
2010 (54)
2023 (48)
2011 (43)
2022 (39)
2013 (37)
2014 (32)
2020 (31)
2012 (31)
2021 (30)
2015 (27)
2018 (17)
2026 (15)
2019 (14)
2017 (12)
2009 (11)
2016 (10)
2008 (7)
2007 (5)
2005 (3)
2004 (1)
2000 (1)

Lab affiliation

School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland (2)
Biomarker Assay Development 1 Novo Nordisk Park 1 Måløv, Denmark (1)
Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Old Road, University of Oxford, Oxford OX3 7LD, UK (1)
Professor School of Biomolecular and Biomedical Science, University College Dublin, School of Biomolecular and Biomedical Science, Conway Institute Belfield Dublin 4 (1)
Richard Dimbleby Laboratory of Cancer Research, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK. UCL Cancer Institute, University College London, London, United Kingdom. Cancer Research UK City of London Centre. GSK (1)
The Rappaport Faculty of Medicine and Research Institute,Technion-Israel Institute of Technology,ISRAEL (1)
University College Dublin, School of Biomolecular and Biomedical Science, Conway Institute Belfield Dublin 4 (1)
Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain (1)

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GDF15 hijacks B cells to fuel the lifeblood of tumor salvage pyrimidine synthesis

B cell-tumor crosstalk has emerged as a critical determinant of tumor progression; however, its role in metabolic reprogramming and therapeutic resistance remains poorly understood. Here, we uncover a metabolic feedback loop that drives resistance to dihydroorotate dehydrogenase (DHODH) inhibitors. ...

2026-09-27 | MTBLS15820 | MetaboLights

Profiling of growth and differentiation factor 15 regulated genes in hepatoma cells

To systematically profile the GDF15-regulated genes in hepatoma cells and to elucidate the possible role of GDF15 on biological processes, high-density oligonucleotide microarrays were hybridized with samples prepared from GDF15- or PBS-treated Huh7.5.1 cells. We found that a total of 894 genes were...

ORGANISM(S): Homo sapiens

2010-11-18 | E-GEOD-25397 | biostudies-arrayexpress

Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia.

Not available

S-EPMC8957514 | biostudies-literature

Role of growth differentiation factor 15 in mouse adipose tissue homeostasis

PRJNA1136038 | ENA

Role of GDF15 (growth and differentiation factor 15) in pulmonary oxygen toxicity.

Not available

S-EPMC4553106 | biostudies-literature

Coordinated Expression of Ras Suppressor 1 (RSU-1) and Growth Differentiation Factor 15 (GDF15) Affects Glioma Cell Invasion.

Not available