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MetabolomicsMetabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei
In vitro culture methods underpin many experimental approaches to biology and drug discovery. The modification of established cell culture methods to be more biologically relevant, or to optimise growth, is traditionally a laborious task. Emerging metabolomics technology enables rapid evaluation of ...
2015-05-14 | MTBLS49 | MetaboLights
MetabolomicsRole of medium in bacterial growth
Not available
ORGANISM(S): Bacteria 
ST000317 | MetabolomicsWorkbench
MetabolomicsRole of medium in bacterial growth (HILIC chromatography)
Not available
ORGANISM(S): Bacteria 
ST000326 | MetabolomicsWorkbench
MetabolomicsHuman oral keratinocytes growth and proliferation based on culture medium volume
Not available
ORGANISM(S): Homo sapiens 
ST000690 | MetabolomicsWorkbench
MetabolomicsMetabolomic changes in growth of E. colik at four timespoints in MOPS rich and minimum medium
Not available
ORGANISM(S): Escherichia coli 
ST002419 | MetabolomicsWorkbench
MetabolomicsGrowth Substrate and Prophage Induction Collectively Influence Metabolite and Lipid Profiles in a Marine Bacterium

Bacterial growth substrates influence a variety of biological functions, including the biosynthesis and regulation of lipid intermediates. The extent of this rewiring is not well understood nor has it been considered in the context of virally-infected cells. Here, we use a one-host-two-temperate ...

2022-08-04 | MTBLS5345 | MetaboLights
MetabolomicsGrowth control of the eukaryote cell: a systems biology study in yeast
Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the transcriptome, proteome, endometabolome and exometabolome of the yeast Saccharomyces cerevisiae. Each function...
2012-04-19 | MTBLS8 | MetaboLights
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
MetabolomicsAnalysis of Growth Phases of Enterotoxigenic Escherichia coli Reveals a Distinct Transition Phase before Entry into Early Stationary Phase with Shifts in Tryptophan, Fucose, and Putrescine Metabolism and Degradation of Neurotransmitter Precursors

Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in children and adults in endemic areas. Gene regulation of ETEC during growth in vitro and in vivo needs to be further evaluated, and here we describe the full transcriptome and metabolome of ETEC dur...

2022-07-15 | MTBLS3540 | MetaboLights
TranscriptomicsLactobacillus plantarum IMDO 130201, a wheat sourdough isolate, adapts to growth in wheat sourdough simulation medium at different pH values through differential gene expression
Sourdough is a very competitive and challenging environment for microorganisms. Usually, a stable microbiota composed of lactic acid bacteria (LAB) and yeasts comes to dominate this ecosystem. Although rich in carbohydrates, thus providing an ideal environment to grow, the low pH presents a particul...
ORGANISM(S): Lactobacillus plantarum 
2011-07-31 | E-GEOD-23945 | biostudies-arrayexpress
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