Sort   by:  
 Page size 
ProteomicsGRP75 in chicken - 75 kDa glucose-regulated protein (GRP75) is a novel molecular signature for heat stress response in avian species
GRP75 is a multipotent chaperone regulating cellular processes ranging from stress response to neurodegeneration. As the only ATPase component of the pre-protein mitochondrial import machinery, GRP75 plays a key role in multiple basic mitochondrial processes, including mitochondrial protein import, ...
ORGANISM(S): Gallus gallus (Chicken) 
2019-12-16 | PXD013591 | Pride
Avian Grp75 And heat stress 
GenomicsEffect of GRP75 deficiency on gene expression in DN3 thymocytes
Effect of GRP75 deficiency on gene expression in DN3 thymocytes
PRJNA1115108 | ENA
GenomicsEffect of GRP75 deficiency on gene expression in different subsets of CD8+ T cells
Effect of GRP75 deficiency on gene expression in different subsets of CD8+ T cells
PRJNA1470610 | ENA
TranscriptomicsEffect of GRP75 deficiency on gene expression in different subsets of CD8+ T cells
The development and functional maintenance of CD8+ T cells are metabolically regulated processes in which mitochondria serve as the central hub. Here, we identify glucose-regulated protein 75 (GRP75) as a critical mitochondrial regulator controlling these processes. Using T cell-specific Hspa9 (enco...
ORGANISM(S): Mus musculus 
2026-07-09 | GSE333264 | GEO
TranscriptomicsEffect of GRP75 deficiency on gene expression in DN3 thymocytes
Mitochondria and endoplasmic reticulum contacts (MERCs) regulate multiple cellular processes including cell survival and differentiation. Based on the observations that MERCs were specifically enriched in the CD4-CD8- double negative (DN) stage, we studied their role in early thymocyte development. ...
ORGANISM(S): Mus musculus 
2024-06-08 | GSE268197 | GEO
TranscriptomicsSingle-cell RNA sequencing of alveolar macrophages in GRP75 knockdown mice with SARS-CoV-2 N protein-induced lung injury
This study investigates the role of GRP75 (Hspa9)-mediated mitochondria-associated membranes (MAMs) in SARS-CoV-2 nucleocapsid (N) protein-induced acute lung injury. Using single-cell RNA sequencing of lung macrophages from control and GRP75 knockdown mice, we demonstrate that N protein promotes GRP...
ORGANISM(S): Mus musculus 
2026-06-01 | GSE318978 | GEO
GenomicsSingle-cell RNA sequencing of alveolar macrophages in GRP75 knockdown mice with SARS-CoV-2 N protein-induced lung injury
Single-cell RNA sequencing of alveolar macrophages in GRP75 knockdown mice with SARS-CoV-2 N protein-induced lung injury
PRJNA1420915 | ENA
UnknownTargeting GRP75 with a Chlorpromazine Derivative Inhibits Endometrial Cancer Progression Through GRP75-IP3R-Ca2+-AMPK Axis.
Not available
S-EPMC11022737 | biostudies-literature
UnknownGRP75 overexpression rescues frataxin deficiency and mitochondrial phenotypes in Friedreich ataxia cellular models.
Not available
S-EPMC6494971 | biostudies-literature
UnknownNuclear GRP75 binds retinoic acid receptors to promote neuronal differentiation of neuroblastoma.
Not available
S-EPMC3194821 | biostudies-literature
Sort   by:  
 Page size