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TranscriptomicsAffymetrix SNP array data for paediatric ependymoma and constitutional DNA
Background: The high incidence of recurrence and unpredictable clinical outcome for paediatric ependymoma reflect the imprecision of current therapeutic staging and need for novel risk stratification markers. Gain of chromosome 1q has been reported as a frequent aberration and correlate of adverse o...
ORGANISM(S): Homo sapiens 
2012-02-09 | E-GEOD-32101 | biostudies-arrayexpress
UnknownClinicopathologic findings predictive of relapse in children with stage III favorable-histology Wilms tumor.
Not available
S-EPMC3595426 | biostudies-literature
TranscriptomicsTranscription profiling of CACNA1E overexpression in human embryonic kidney HEK293 cells to investigate the involvement of CACNA1E in Wilms tumorigenesis
Wilms tumour (nephroblastoma) is the most common paediatric renal tumour, affecting 1 in 10,000 children. Despite the excellent survival of patients treated with a combination of surgery, chemotherapy and radiotherapy, approximately 15% will relapse and die of this disease. We have identified CACNA1...
ORGANISM(S): Homo sapiens 
2006-12-01 | E-MEXP-587 | biostudies-arrayexpress
UnknownImpact of Surveillance Imaging Modality on Survival After Recurrence in Patients With Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group.
Not available
S-EPMC6269130 | biostudies-literature
UnknownTreatment of Stage IV Favorable Histology Wilms Tumor With Lung Metastases: A Report From the Children's Oncology Group AREN0533 Study.
Not available
S-EPMC6075846 | biostudies-literature
UnknownOutcome and Prognostic Factors in Stage III Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group Study AREN0532.
Not available
S-EPMC5773840 | biostudies-literature
TranscriptomicsThe miR-17/92 Polycistron Is Up-regulated in Sonic Hedgehog-Driven Medulloblastomas and Induced by N-myc in Sonic Hedgehogâ??Treated Cerebellar Neural Precursors
Medulloblastoma is the most common malignant pediatric brain tumor, and mechanisms underlying its development are poorly understood. We identified recurrent amplification of the miR-17/92 polycistron proto-oncogene in 6% of pediatric medulloblastomas by high-resolution single-nucleotide polymorphism...
ORGANISM(S): Homo sapiens 
2010-04-14 | E-GEOD-21166 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of very low risk Wilms Tumors show distinctive gene expression, histologic, and clinical features
The goal of this study is to define biologically distinct subsets of Very Low Risk Wilms Tumors (VLRWT) using oligonucleotide arrays. Description: 52 tumors from the original case:cohort of 600 tumors from NWTS-5 met the criteria for VLRWT. Thirteen tumors were excluded for quality control reasons...
ORGANISM(S): Homo sapiens 
2010-01-19 | E-GEOD-14767 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of kidney samples from Wilms tumor patients to examine down- and up-regulation of genes either side of 1p13 breakpoints
Wilms tumour karyotypes frequently exhibit recurrent, large-scale chromosomal imbalances, among the most common of which are concurrent loss of 1p and gain of 1q. We have previously identified a novel breakpoint at 1p13 by 1Mb-spaced array CGH, and undertook a fine-tiling oligonucleotide array appro...
ORGANISM(S): Homo sapiens 
2007-03-21 | E-TABM-164 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of kidney samples from Wilms tumor patients to accurately map 1p13 breakpoints
Wilms tumour karyotypes frequently exhibit recurrent, large-scale chromosomal imbalances, among the most common of which are concurrent loss of 1p and gain of 1q. We have previously identified a novel breakpoint at 1p13 by 1Mb-spaced array CGH, and undertook a fine-tiling oligonucleotide array appro...
ORGANISM(S): Homo sapiens 
2007-03-21 | E-TABM-155 | biostudies-arrayexpress
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