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ProteomicsA proteomic view of WT and △YdiU Salmonella Typhimurium under iron deficiency condition
Transition metal iron is essential for bacterial survival and growth. For pathogenic bacteria, this challenge is even more severe since human and other mammals have evolved a complicated mechanism of nutritional immunity to restrict iron availability. Preliminary research findings that iron deficien...
ORGANISM(S): Salmonella typhimurium (strain 14028s / SGSC 2262) 
2022-04-27 | PXD023378 | Pride
Differential protein expression  iron deficiency  wt and △ydiu 
UnknownSNRNP70 regulates the splicing of CD55 to promote osteosarcoma progression.
Not available
S-EPMC11665567 | biostudies-literature
ProteomicsProteomic data of ovary of OHSS model rat
The mass spectrometer was used to identify the labeled samples from electroacupuncture treated and Ovarian Hyper-stimulation Syndrome (OHSS) group. The ovarian proteins from four biological replicates in each group were extracted using the phenolic extraction method, iTRAQ labeling and quantitative ...
ORGANISM(S): Rattus Rattus 
2021-01-10 | PXD023493 |
UnknownGTSE1-expressed osteoblastic cells facilitate formation of pro-metastatic tumor microenvironment in osteosarcoma.
Not available
S-EPMC12359159 | biostudies-literature
MetabolomicsEnterohepatic Axis Reprogramming via S1PR2 Inhibition Activates Compensatory Microbiota-Bile Acid Crosstalk to Ameliorate Colitis

Studies have revealed that gut microbiota dysbiosis and bile acid metabolism play pivotal roles in the pathogenesis of inflammatory bowel disease, and there exists a reciprocal interaction between gut microbiota and bile acid metabolism. S1PR2, a G protein-coupled receptor, has been demonstrated...

2025-12-19 | MTBLS13508 | MetaboLights
ProteomicsHigh-Throughput Intact Glycopeptide Quantification Strategy with Targeted-MS (HTiGQs-Target) Reveals Site-Specific IgG N-Glycopeptides as Biomarkers for Hepatic Disorder Diagnosis and Staging
We developed a high-throughput targeted quantification strategy for intact glycopeptides (HTiGQs-Target) to diagnose and differentiate the malignancy of liver diseases. The method involves two-step labeling. This step derivatization makes the same parent ions in different samples produce sufficient ...
ORGANISM(S): Homo Sapiens 
PXD042528 |
TranscriptomicsInitiation Pausing of 80S Ribosome on mRNA Is Governed by 5’UTR and Responsive to mTORC1 Signaling (Microarray)
Recent studies have revealed that the mRNA translation is punctuated by ribosomal pauses through the body of transcripts. However, little is known about its physiological significance and regulatory aspects. Here we present a multi-dimensional ribosome profiling approach to quantify the dynamics o...
ORGANISM(S): Mus musculus 
2011-11-12 | E-GEOD-25331 | biostudies-arrayexpress
ProteomicsBiological characteristics of cefiderocol-resistant Klebsiella pneumoniae and the mechanism of reduced biofilm-forming ability—From the perspective of proteome and transcriptome
In the present study, we collected cefiderocol 16 resistant K. pneumoniae isolates during a 36-day acclimatization procedure while increasing the 17 cefiderocol concentration in the culture medium. Strains were studied for changes in their 18 biological characteristics using proteomics and transcrip...
ORGANISM(S): Klebsiella Pneumoniae Subsp. Pneumoniae Ntuh-k2044 
PXD028717 |
TranscriptomicsInitiation Pausing of 80S Ribosome on mRNA Is Governed by 5'UTR and Responsive to mTORC1 Signaling (RNA-Seq)
Recent studies have revealed that the mRNA translation is punctuated by ribosomal pauses through the body of transcripts. However, little is known about its physiological significance and regulatory aspects. Here we present a multi-dimensional ribosome profiling approach to quantify the dynamics o...
ORGANISM(S): Mus musculus 
2011-11-12 | E-GEOD-25626 | biostudies-arrayexpress
ProteomicsCD229 promotes multiple myeloma cell proliferation by regulating RAS/ERK pathway
Flag antibody was used for immunoprecipitation, and cd229-OE partial binding protein was searched by protein spectrum in CD229-OE multiple myeloma cell line, and its interaction was analyzed.
ORGANISM(S): Homo Sapiens 
2022-03-09 | PXD032177 |
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