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GenomicsGenome-wide mapping of Nr5a2 in mouse embryonic stem cells
Nr5a2 (also known as liver receptor homolog-1, Lrh-1) has been shown to bind both the proximal enhancer and proximal promoter regions of Pou5f1 and regulate Pou5f1 in the epiblast stage of mouse embryonic development (Gu et al., 2005). Nr5a2-null embryos display a loss of Oct4 expression in the epib...
ORGANISM(S): Mus musculus 
2010-01-22 | E-GEOD-19019 | biostudies-arrayexpress
TranscriptomicsC. elegans piRNAs are processed from capped-small RNAs transcribed at promoters throughout the genome
Piwi-interacting (pi) RNAs are a class of germline-expressed small RNAs that have been linked to epigenetic programming in metazoa. C. elegans piRNAs known as 21U-RNAs are defined by more than 15,000 genome-encoded species. To explore the origin of 21U-RNAs we employed methods to enrich the 5' ends ...
ORGANISM(S): Mus musculus 
2012-12-22 | E-GEOD-40053 | biostudies-arrayexpress
UnknownPrognostic value of components of body composition in patients treated with targeted therapy for advanced renal cell carcinoma: a retrospective case series.
Not available
S-EPMC4323238 | biostudies-literature
MetabolomicsL-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)

The overuse of antibiotics has made public health and safety face a serious crisis. It is urgent to develop new clinical treatment methods to combat drug-resistant bacteria to alleviate the health crisis. The efficiency of antibiotics is closely related to the metabolic state of bacteria. However...

2023-05-02 | MTBLS7711 | MetaboLights
MetabolomicsL-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)

The overuse of antibiotics has made public health and safety face a serious crisis. It is urgent to develop new clinical treatment methods to combat drug-resistant bacteria to alleviate the health crisis. The efficiency of antibiotics is closely related to the metabolic state of bacteria. However...

2023-05-02 | MTBLS7713 | MetaboLights
UnknownImmunoreactivity of Plasminogen Activator Inhibitor 1 and Its Correlation with Dysmenorrhea and Lesional Fibrosis in Adenomyosis.
Not available
S-EPMC8289782 | biostudies-literature
TranscriptomicsDiverse pathways generate microRNA-like RNAs and Dicer-independent small interfering RNAs in fungi
A variety of small RNAs, including the Dicer-dependent miRNAs and the Dicer-independent Piwi-interacting RNAs, associate with Argonaute family proteins to regulate gene expression in diverse cellular processes. These two species of small RNA have not been found in fungi. Here, by analyzing small RN...
ORGANISM(S): Neurospora crassa 
2010-07-01 | E-GEOD-21175 | biostudies-arrayexpress
UnknownEarly skeletal muscle loss during target therapy is a prognostic biomarker in metastatic renal cell carcinoma patients.
Not available
S-EPMC5548774 | biostudies-literature
UnknownMechanisms of indigo naturalis on treating ulcerative colitis explored by GEO gene chips combined with network pharmacology and molecular docking.
Not available
S-EPMC7495487 | biostudies-literature
UnknownNutritional screening is strongly associated with overall survival in patients treated with targeted agents for metastatic renal cell carcinoma.
Not available
S-EPMC4575553 | biostudies-literature
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