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ProteomicsTMTs-based quantitative proteomic reveals the potential targets of a novel probiotic mixture on seasonal allergic rhinitis
This study examines the effect of a novel multistrain probiotic mixture on symptoms of allergic rhinitis (AR) and investigate potential targets underlying the probiotic treatment using proteomics. All engaged participants in our study are provided with informed consent, and the study design was appr...
ORGANISM(S): Homo Sapiens 
2023-09-28 | PXD045758 |
ProteomicsGelatin/lignin hydrogel loaded with mesenchymal stem cell-derived exosomes enriched in microRNA-185 inhibits progression of oral cancer
Purpose: Due to the lack of effective local therapeutic strategies for oral squamous cell carcinoma (OSCC), this study aimed to develop a novel gelatin/lignin hydrogel loaded with mesenchymal stem cell (MSC) derived exosomes enriched in microRNA-185 (miR-185 EV) for intraoral delivery, followed by s...
ORGANISM(S): Homo Sapiens 
2025-12-31 | PXD072609 |
UnknownVHL regulates the sensitivity of clear cell renal cell carcinoma to SIRT4-mediated metabolic stress via HIF-1α/HO-1 pathway.
Not available
S-EPMC8209205 | biostudies-literature
TranscriptomicsMicroRNAome of porcine prenatal and postnatal development.
Sus scrofa (pig, or swine) is one of the most important economic animals and a close biological model for complex human diseases such as obesity and diabetes. It is therefore utterly important to decode the porcine microRNAome (miRNAome) as in the literature only a small portion of it is known. In t...
ORGANISM(S): Sus scrofa 
2010-02-27 | E-GEOD-17885 | biostudies-arrayexpress
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
MetabolomicsLactation-related metabolic mechanism investigated based on mammary gland metabolomics and 4 biofluids’ metabolomics relationships in dairy cows

BACKGROUND: Lactation is extremely important for dairy cows; however, the understanding of the underlying metabolic mechanisms is very limited. This study was conducted to investigate the inherent metabolic patterns during lactation using the overall biofluid metabolomics and the...

2018-03-16 | MTBLS411 | MetaboLights
ProteomicsAI-empowered integrative structural characterization of m6A writer complex
Investigation into the structure of the human m6A writer complex.
ORGANISM(S): Homo Sapiens 
2022-08-18 | PXD036144 |
ProteomicsApical anchorage and stabilization of subpellicular microtubules by apical polar ring ensures Plasmodium ookinete infection in mosquito
Morphogenesis of many protozoans depends on a polarized establishment of cortical cytoskeleton possessing the subpellicular microtubules (SPMTs), which are apically nucleated and anchored by the apical polar ring (APR). In the malaria parasite Plasmodium, APR can be observed when a round zygote diff...
ORGANISM(S): Plasmodium Yoelii Yoelii 17xnl 
2022-11-18 | PXD038209 |
UnknownIdentification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
Not available
S-EPMC2212820 | biostudies-literature
UnknownGlobal, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019.
Not available
S-EPMC10507198 | biostudies-literature
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