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ProteomicsThe UGT2B17 metabolic pathway as a key determinant of liver homeostasis: evidence from the hepatic proteome of individuals naturally deficient in UGT2B17
One of the most crucial pathways involved in the metabolism and detoxification of drugs and endobiotics is the glucuronidation process, primarily occurring in the liver. This pathway is catalyzed by glycosyltransferases comprising 22 enzymes such as UGT2B17, which is entirely absent in a large propo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000095873 | MassIVE
ProteomicsAndrogenic Effects of 11-oxyandrogens in Castration-Resistant Prostate Cancer
Investigations of CRPC cell models demonstrate that 11-ketotestesterone (11KT) and 11-hydroxytestosterone (11OHT) drive robust AR-mediated proliferative responses and significantly modulate gene and protein expression profiles, paralleling canonical androgens. They also exhibit unique transcriptiona...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-05-13 | MSV000097860 | MassIVE
TranscriptomicsGene expression analysis upon UGT1A_i2 knockdown
Evaluate modulation in gene expression modulation upon UGT1A_i2 knockdown in basal conditions and also under pharmacological treatment (SN-38) 6 samples in duplicate (12 samples total); HT115 colorectal cell line was infected with either UGT1A_i2 shRNA or non-target shRNA and left untreated or treat...
ORGANISM(S): Homo sapiens 
2014-01-08 | E-GEOD-48118 | biostudies-arrayexpress
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