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TranscriptomicsTranscription profiling of brain, liver and spleen from rats infected with Escherichia coli K1 and treated with capsule-selective endosialidase E
Transcription profiling of infected and treated (Capsule-Selective Endosialidase E Minimizes) of RNA isolated from brain/spleen/liver of rats with E.coli K1
ORGANISM(S): Rattus norvegicus 
2010-01-10 | E-MEXP-2406 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of heart left ventricles from 15 week old inbred COP, DA, and F1(COP x DA) offspring with respect to aerobic running capacity (low, high, and intermediate performers respectively)
We used high density oligonucleotide arrays to measure the relative expression levels of ~27,000 probe sets in the left ventricles of inbred rat strains; DA (high performing), Copenhagen (COP, low performing), as well as F1(COPxDA) rats bred from these tw
ORGANISM(S): Rattus norvegicus 
2007-09-13 | E-GEOD-1795 | biostudies-arrayexpress
UnknownA PET-CT study on neuroinflammation in Huntington's disease patients participating in a randomized trial with laquinimod.
Not available
S-EPMC10069663 | biostudies-literature
TranscriptomicsTranscription profiling of rat gastric ECL cells during 24 hrs fasting
Gastric ECL cells and parietal (PC) cells in normal conditions and gastric ECL cells after 24 hrs fasting were purified using a combination of counter-flow elutriation, nycodenz gradient and FACS based on acridine orange labeling of histamine containing vesicles (ECL cells) or autofluorescense (PC c...
ORGANISM(S): Rattus norvegicus 
2008-06-14 | E-GEOD-6204 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression in rat lung receiving chemopreventive agents and attenuation of cigarette smoke-induced alterations
We previously showed that exposure of rats to environmental cigarette smoke (ECS) causes extensive downregulation of microRNA expression in the lung, resulting in overexpression of multiple genes and proteins. In the present study, we evaluated by microarray the expression of 484 microRNAs in the l...
ORGANISM(S): Rattus norvegicus 
2010-05-16 | E-GEOD-19540 | biostudies-arrayexpress
TranscriptomicsThe effect of GW3965 and dexamethasone on gene expression of rat livers
GLUCOCORTICOIDS are steroid hormones that strongly influence intermediary carbohydrate metabolism by increasing the transcription rate of glucose-6-phosphatase (G6Pase) a key enzyme of gluconeogenesis, and suppress the immune system which makes them one of the most important therapeutic agents in th...
ORGANISM(S): Rattus norvegicus 
2012-04-01 | E-GEOD-29912 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat testis by transplacental exposure to estrogen receptor (ER) agonists - high and low doses of 17a-Ethynyl estradiol, genistein or bisphenol A
The purpose of this study was to determine 1) the transcriptional program elicited by exposure to three estrogen receptor (ER) agonists: 17 a-ethynyl estradiol (EE), genistein (Ges) and bisphenol A (BPA) during fetal development of the rat testis and epididymis; and 2) whether very low dosages of es...
ORGANISM(S): Rattus norvegicus 
2005-05-18 | E-TABM-12 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of baby rat kidney cells transformed with the non-oncogenic Ad5 E1 or oncogenic Ad12 E1 region, as well as primary untransformed BRK cells
Multiple rat microarrays were used to compare RNA transcript levels from 15,481 genes of baby rat kidney (BRK) cells transformed with the non-oncogenic Ad5 E1 or oncogenic Ad12 E1 region, as well as primary untransformed BRK cells.
ORGANISM(S): Rattus norvegicus 
2008-06-20 | E-MTAB-30 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of 61 Salmonella enterica serovar Typhimurium isoltates to identify hotspots in genome variation and distinguish between different isolates from the same geographical region
A collection of 61 Salmonella enterica serovar Typhimurium (S. Typhimurium) of animal and human origin, matched as closely as possible by phage type, antimicrobial resistance pattern and place / time of isolation, and sourced from farms or hospitals in Scotland, were analysed by antimicrobial suscep...
ORGANISM(S): Salmonella enterica serotype Typhimurium 
2007-06-09 | E-SGRP-6 | biostudies-arrayexpress
TranscriptomicsExpression profiling of brain structures of dependent and non-dependent rats self-administering alcohol and naive controls
Rats were trained to orally self-administer alcohol in a concurrent, two-lever, free-choice contingency using a modification of the sweet solution fading procedure (O'Dell et al., 2004; Roberts et al., 2000; Vendruscolo et al., 2012). Following acquisition of self-administration, rats were allowed t...
ORGANISM(S): Rattus norvegicus 
2014-11-13 | E-GEOD-60966 | biostudies-arrayexpress
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