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ProteomicsPharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis
Protein tyrosine phosphatase mitochondrial 1 (PTPMT1), is a member of the protein tyrosine phosphatase superfamily localized on the mitochondrial inner membrane, and regulates the biosynthesis of cardiolipin. Given the important position of PTPMT1 in mitochondrial function and metabolism, pharmacolo...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058606 | Pride
Ptpmt1  mitochondria  ferroptosis  tca cycle  hepatocellular carcinoma 
ProteomicsPotential binding proteins of CAV3 obtained from LC-MS/MS
To gain further insight into the molecular mechanisms of CAV3 in DCM. we conducted liouid chromatography-tandem mass spectrometry (LC-MS/MSassays to identify potential binding proteins of CAV3 in cardiomyocytes.LC-MS/MS was conducted by SpecAly Life Technology Co, Ltd. (Wuhan, China).
ORGANISM(S): Homo Sapiens 
2023-08-21 | PXD044674 |
ProteomicsAI-facilitated multi-omics reveal TRF-controlled propionylation in determining protein homeostasis
Firstly, we systematically identified rhythmically modified Kpr sites, through time-series propionylomic profiling of fly heads. Wild-type (WT) and per0 flies were entrained under light/dark cycles (LD) and then released into constant darkness (DD), respectively. On the first day of DD, whole heads ...
ORGANISM(S): Drosophila Melanogaster 
2023-03-20 | PXD040987 |
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