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UnknownEntecavir vs lamivudine therapy for naive patients with spontaneous reactivation of hepatitis B presenting as acute-on-chronic liver failure.
Not available
S-EPMC4000512 | biostudies-literature
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
ProteomicsProteomic Characterization of Epithelial Ovarian Cancer Delineates Molecular Signatures and Therapeutic Targets in Distinct Histological Subtypes
Clear cell carcinoma (CCC), endometrioid carcinoma (EC), and serous carcinoma (SC) are the major histological subtypes of epithelial ovarian cancer (EOC), whose differences in carcinogenesis are still unclear. Here, we undertake comprehensive proteomic profiling of 80 CCC, 79 EC, 80 SC, and 30 contr...
ORGANISM(S): Homo sapiens (Human) 
2023-10-30 | PXD033741 | Pride
Epithelial ovarian cancer proteomics histological subtype tumor biomarkers drug target 
ProteomicsIdentification of targets of DBIC
Pyroptosis is a type of lytic cell death executed by members of the gasdermin family. It has been demonstrated that induction of pyroptosis can effectively inhibit tumor growth, which implicates a new strategy for clinical tumor therapy, especially for those tumors (such as melanoma) that are insens...
ORGANISM(S): Homo sapiens (Human) 
2025-11-21 | PXD054435 | Pride
Nuclear receptor nur77  heme  granzyme b  gsdmc  pyroptosis 
UnknownDisruption of heme homeostasis by nuclear receptor Nur77 induces pyroptosis through granzyme B-dependent GSDMC cleavage.
Not available
S-EPMC12711971 | biostudies-literature
UnknownProteomic characterization of epithelial ovarian cancer delineates molecular signatures and therapeutic targets in distinct histological subtypes.
Not available
S-EPMC10684593 | biostudies-literature
UnknownImprovement cues of lesion absorption using the adjuvant therapy of traditional Chinese medicine Qinbudan tablet for retreatment pulmonary tuberculosis with standard anti-tuberculosis regimen.
Not available
S-EPMC7203794 | biostudies-literature
ProteomicsEvaluation of library-free strategies for phosphoproteomics and ubiquitinomics data-independent acquisition data
Phosphoproteomics and ubiquitinomics data-independent acquisition MS data is generally analyzed using a DDA spectral library. Performance of different library-free strategies of analyzing phosphoproteomics and ubiquitinomics DIA MS data are not evaluated. In this study, we assess three library-free ...
ORGANISM(S): Homo Sapiens 
PXD037870 |
ProteomicsGut microbiota may underlie the predisposition of healthy individuals to COVID-19
The COVID-19 pandemic is spreading globally with high disparity in the susceptibility of the disease severity. Identification of the key underlying factors for this disparity is highly warranted. Here we describe constructing a proteomic risk score based on 20 blood proteomic biomarkers which predic...
ORGANISM(S): Homo Sapiens 
2020-06-09 | PXD019675 |
Unknown<i>ROBO1</i> deficiency impairs HSPC homeostasis and erythropoiesis via <i>CDC42</i> and predicts poor prognosis in MDS.
Not available
S-EPMC12488054 | biostudies-literature
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