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MetabolomicsMetabolomics Identifies Metabolic Markers of Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes
Cardiovascular disease is a leading cause of death worldwide. Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) hold immense clinical potential and recent studies have enabled generation of virtually pure hPSC-CMs with high efficiency in chemically defined and xeno-free conditions. Despi...
2018-04-24 | MTBLS425 | MetaboLights
MetabolomicsThe Poly (ADP-Ribose) Polymerase inhibitor Veliparib and Radiation Cause Significant Cell Line Dependent Metabolic Changes in Breast Cancer Cells
Breast tumors are characterized into different subtypes based on their surface marker expression, which affects their prognosis and treatment. For example, triple negative breast cancer cells (ER-/PR-/Her2-) show reduced susceptibility towards radiotherapy and chemotherapeutic agents. Poly (ADP-ribo...
2016-11-07 | MTBLS337 | MetaboLights
UnknownGenotype-Guided Dosing of Warfarin in Chinese Adults: A Multicenter Randomized Clinical Trial.
Not available
S-EPMC7439928 | biostudies-literature
UnknownComparison of nipple sparing and skin sparing mastectomy with immediate reconstruction based on patient reported outcomes.
Not available
S-EPMC12041335 | biostudies-literature
UnknownThe multifaceted roles of long noncoding RNAs in pancreatic cancer: an update on what we know.
Not available
S-EPMC7003405 | biostudies-literature
UnknownIntraductal chemotherapy for triple-negative breast cancer: a pathway to minimally invasive clinical treatment.
Not available
S-EPMC11837698 | biostudies-literature
TranscriptomicsDifferential gene expression in resistant and susceptible peanut cultivars during Aspergillus infection
To identify peanut Aspergillus-interactive and Aspergillus-resistance genes, we carried out a large scale peanut Expressed Sequence Tag (EST) project followed by a peanut microarray study. For expression profiling, resistant and susceptible peanut cultivars were infected with a mixture of Aspergill...
ORGANISM(S): Arachis hypogaea 
2011-07-31 | E-GEOD-27612 | biostudies-arrayexpress
ProteomicsChronic exposure to low-level lipopolysaccharide dampens influenza-mediated inflammatory response via A20 and PPAR network
Influenza A virus (IAV) infection leads to severe inflammation, and while epithelial-driven inflammatory responses occur via activation of NF-B, the factors that modulate inflammation, particularly the negative regulators are less well-defined. In this study we show that A20 is a crucial molecular...
ORGANISM(S): Homo Sapiens 
PXD035611 |
ProteomicsComprehensive analysis of individual variation in the urinary proteome revealed significant gender differences
To elucidate the individual variation and related factors influencing the urinary proteome, we comprehensively analyzed the urine samples from healthy adult donors (aged 20-69 years). Co-expression network analysis revealed protein clusters representing the metabolic status, gender-related differenc...
ORGANISM(S): Homo Sapiens 
PXD013949 |
ProteomicsA global multi-regional proteomic map of the human cerebral cortex
In this study, four groups of the iTRAQ quantification experiment using 2D-LC-MS/MS analysis, one group of the label-free quantification experiment using 2D-LC-MS/MS analysis, one group of the PRM quantification experiment of the human brain tissue were included. Therefore, six subprojects are incl...
ORGANISM(S): Homo Sapiens 
2021-03-09 | PXD024613 |
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